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CHO-K1/MT1/Gα15 Stable Cell Line

CHO-K1/MT1/Gα15 Stable Cell Line

Item no.	M00424
Manufacturer	GenScript
Amount	2 vials
Category	Metabolism Glucose Homeostasis Cell Lines & Cell Culture Cell Lines
Type	Cell line
Specific against	other
Dry ice	Yes
ECLASS 10.1	42040401
ECLASS 11.0	42040401
UNSPSC	41106509
Alias	molecule/M00424-MT1,
Similar products	CHO-K1/MT1/Galpha15
Shipping Condition	Dry ice
Available
Manufacturer - Category	Cellular Analysis
Country of Origin	USA
Shipping Temperature	-80°C
Storage Conditions	-196°C
Product Line	GPCR Cell Lines
Manufacturer - portfolio	Cell Line (CPBU)
Description	Melatonin binds to two specific G-protein coupled receptors (GPCR), MT1 (MTNR1A/MEL1A) and MT2 (MTNR1B/MEL1B). MT1 receptors signal via inhibitory G proteins (Galpha_i and Galpha_o) leading to adenylate cyclase inhibition and possibly inositol phosphate stimulation in recombinant systems. In certain native tissues (e.g. sheep pars tuberalis, rat cerebral and caudal arteries) melatonin responses are presumably mediated through activation of MT1 receptors. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.