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β-Amyloid (1-42), human

β-Amyloid (1-42), human

Manufacturer	GenScript
Category	Oncology Neuroscience Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding By Cell Type Peptides & Proteins Obesity Adenocarcinoma Lipid & Fatty Acid Transport Peptides
Type	Peptides
Specific against	Human
Amount	1 mg
Item no.	RP10017-1
Targets	APOE, APP
eClass 6.1	34160400
eClass 9.0	32160409
Available
Description	This peptide is well suited to the quantitative determination of A 42 peptide. Alzheimer’s disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein component of these plaques is beta amyloid peptide (A), a 40- to 43- amino-acid peptide cleaved from amyloid precursor protein by secretase (BACE) and a putative (gamma) secretase. Increased release of the ‘longer forms’ of A peptide, A 42 and A 43, which have a greater tendency to aggregate than A 40, occurs in individuals expressing certain genetic mutations, expressing certain ApoE alleles or may other, still undiscovered factors.
Notes	This product is a chemically-modified beta-amyloid (1-42) precursor, which belongs to GenScript’s "click peptides".The "click peptides" are best described by the following key features: 1. Enhanced Stability—The O-acyl moiety within the click peptide is stable even under acidic pH. 2. Convenient and quick process—The "click peptides" can be easily converted to native peptide at pH 7.4 or above. 3. No by-product formation in the conversion process 4. High Solubility in water compared to the native peptide. 5. Superior quality—After the "click", the aggregative property of the peptides is significantly minimized compared to its native format.
Solubility	Soluble in water
Storage	Store at -20C
Manufacturers Category	Peptides & Chemicals
Manufacturers Product Line	Amyloid Peptides
Product Origin	USA

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

RP10017-1-datasheet.pdf

RP10017-1-safety-datasheet.pdf