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Fibrinogen Binding Inhibitor Peptide European Partner

Item no. RP10832-5
Manufacturer GenScript
Amount 5 mg
Quantity options 1 mg 5 mg
Category
Type Peptides
Specific against other
Purity > 95%
Sequence HHLGGAKQAGDV ; {HIS}{HIS}{LEU}{GLY}{GLY}{ALA}{LYS}{GLN}{ALA}{GLY}{ASP}{VAL}
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias peptide/RP10832-Fibrinogen_Binding_Inhibitor_ Peptide, Fibrinogen Binding Inhibitor Peptide, a synthetic dodecapeptide, represents the specific platelet receptor recognition site of the human fibrinogen g-chain (residues 400-411). It is also a potent inhibitor of the binding of fibrinogen, fibronectin, and von Willebrand factor to thrombin- or ADP-stimulated platelets. Fibrinogen Binding Inhibitor Peptide has been used in studying phosphorylation processes associated with platelet activation. </td></tr><tr><th>Solubility</th><td colspan="7"> Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. </td></tr><tr><th>Purity</th><td colspan="7"> > 95% </td></tr><tr><th>Storage</th><td colspan="7"> Before using, store the peptide in the DRY form at 0-5C. For best and repeatable results, rehydrate the peptide immediately before using. Do not re-freeze any unused portions. </td></tr><tr><th>Notes</th><td colspan="7"> In activated platelets, single gamma 400-411 sequence is no longer required for initiation of adhesion but becomes sufficient for firm adhesion. In contrast to the binding of whole fibrinogen, binding of fragment 400-411 does not lead to tyrosine phosphorylation for platelet proteins.</td></tr>
Similar products Fibrinogen
Available
Country of Origin
USA
Storage Conditions
Before using, store the peptide in the DRY form at 0-5C. For best and repeatable results, rehydrate the peptide immediately before using. Do not re-freeze any unused portions.
Description
Fibrinogen Binding Inhibitor Peptide, a synthetic dodecapeptide, represents the specific platelet receptor recognition site of the human fibrinogen g-chain (residues 400-411). It is also a potent inhibitor of the binding of fibrinogen, fibronectin, and von Willebrand factor to thrombin- or ADP-stimulated platelets. Fibrinogen Binding Inhibitor Peptide has been used in studying phosphorylation processes associated with platelet activation.
Solubility
Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
Notes
In activated platelets, single gamma 400-411 sequence is no longer required for initiation of adhesion but becomes sufficient for firm adhesion. In contrast to the binding of whole fibrinogen, binding of fragment 400-411 does not lead to tyrosine phosphorylation for platelet proteins.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 mg
Available: In stock
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