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Endomorphin-1

Endomorphin-1

Item no.	RP10925
Manufacturer	GenScript
Amount	5 mg
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience By Cell Type Carcinoma Peptides & Proteins Peptides
Type	Peptides
Specific against	other
Purity	> 95%
Sequence	YPWF-NH2 ; {TYR}{PRO}{TRP}{PHE}-NH2
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	peptide/RP10925-Endomorphin-1_EM-1_YPWF-NH2, Endomorphin-1 (EM-1) is a recently isolated endogenous peptide having potent analgesic activity and high affinity and selectivity for the mu-opioid receptor. Endomorphin-1 activates G proteins and inhibits adenylyl cyclase activity in membrane preparations from cells stably expressing the mu opioid receptor, an effect reversed by the mu receptor antagonist CTAP (D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2). However, endomorphin-1 appears to have no influence on cells stably expressing the delta opioid receptor. </td></tr><tr><th>Solubility</th><td colspan="7"> The peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents. </td></tr><tr><th>Purity</th><td colspan="7"> > 95% </td></tr><tr><th>Storage</th><td colspan="7"> Store the peptide at -20C. Keep container tightly closed.</td></tr><tr><th>Notes</th><td colspan="7"> Endomorphin-1 is a potent, selective endogenous u opioid receptor agonist.</td></tr>
Similar products	Endomorphin-1
Available
Country of Origin	USA
Storage Conditions	Store the peptide at -20C. Keep container tightly closed.
Description	Endomorphin-1 (EM-1) is a recently isolated endogenous peptide having potent analgesic activity and high affinity and selectivity for the mu-opioid receptor. Endomorphin-1 activates G proteins and inhibits adenylyl cyclase activity in membrane preparations from cells stably expressing the mu opioid receptor, an effect reversed by the mu receptor antagonist CTAP (D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2). However, endomorphin-1 appears to have no influence on cells stably expressing the delta opioid receptor.
Solubility	The peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents.
C-Terminal	NH2
Notes	Endomorphin-1 is a potent, selective endogenous u opioid receptor agonist.

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