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Bradykinin (1-5)

Bradykinin (1-5)

Item no.	RP11131-25
Manufacturer	GenScript
Amount	25.0 mg
Quantity options	25.0 mg 5 mg
Category	Oncology By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Peptides
Type	Peptides
Specific against	other
Purity	> 95%
Sequence	RPPGF ; {ARG}{PRO}{PRO}{GLY}{PHE}
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	peptide/RP11131-Bradykinin_1-5_RPPGF, The bradykinin (BK) fragment (1-5) (RPPGF) is among the most stable of naturally occurring metabolites. Bradykinin (1-5) may be used as a marker for BK production, in vivo . It is known that an intact Arg residue in the C-terminus is required for certain biological activities. BK 1-5 is the smallest peptide that can inhibit alpha-thrombin-induced platelet aggregation and secretion and calcium mobilization. Bradykinin (1-5) also prevents alpha-thrombin from cleaving the thrombin receptor peptide, NATLDPRSFLLR, between arginine and serine. Such antithrombin activities of BK 1-5 may contribute to the cardioprotective nature of kinins. </td></tr><tr><th>Purity</th><td colspan="7"> > 95% </td></tr><tr><th>Storage</th><td colspan="7"> Store the peptide at -20C </td></tr>
Similar products	Bradykinin
Available
Country of Origin	USA
Storage Conditions	Store the peptide at -20C
Description	The bradykinin (BK) fragment (1-5) (RPPGF) is among the most stable of naturally occurring metabolites. Bradykinin (1-5) may be used as a marker for BK production, in vivo . It is known that an intact Arg residue in the C-terminus is required for certain biological activities. BK 1-5 is the smallest peptide that can inhibit alpha-thrombin-induced platelet aggregation and secretion and calcium mobilization. Bradykinin (1-5) also prevents alpha-thrombin from cleaving the thrombin receptor peptide, NATLDPRSFLLR, between arginine and serine. Such antithrombin activities of BK 1-5 may contribute to the cardioprotective nature of kinins.

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