Comparison

IL-2, Human  European Partner

Manufacturer GenScript
Category
Type Proteins
Specific against Human
Amount 10 ug
Item no. Z00368-10
Targets PRKD1, MAPK1, FOXD3, CD262, CD24, IL2
eClass 6.1 34160400
eClass 9.0 42020190
Available
Specificity
The specific activity as determined and was found to be greater than 1.0x107 IU/mg.
Description
In vitro, studies performed on human cell lines demonstrate the immunoregulatory properties of Interleukin-2 (IL-2) including: 1) enhancement of lymphocyte mitogenesis and stimulation of long-term growth of human Interleukin-2 (IL-2) dependent edll lines, 2) enhancement of lymphocyte cytotoxicity, 3) induction of killer cell (lymphokine-activated (LAK) and natural (NK)) activity, 4) induction of interferon-gamma production. Recombinant human Interleukin-2 (IL-2), is a highly purified protein with a molecular weight of approximately 15, 300 Da. The chemical name is des-alanyl-1, serine-125 human interleukin-2. It is produced by recombinant DNA technology using a genetically engineered, E. coli, strain containing an analog of the human Human Interleukin-2 (IL-2) gene. Genetic engineering techniques were used to modify the human Interleukin-2 (IL-2) gene, and the resulting expression clone encodes a modified human Interleukin-2 (IL-2). This recombinant form differs from native Interleukin-2 (IL-2) in following ways: 1) it is not glycosylated, 2) the molecule has no N-terminal alanine, 3) the molecule has serine substituted for cysteine at amino acid position 125, 4) the aggregation state of molecule is likely to be different from that of native Interleukin-2 (IL-2).
Endotoxin Level
Less than 0.1 ng/ug (1 EU/ug) of recombinant human Interleukin-2 (IL-2) as determined by LAL test.
Formulation
The protein was lyophilized after extensive dialysis against 50mM Phosphate buffer, pH7.5, 5% Mannitol buffer.
M.W.
15, 300 Da
Product Line
Cytokine, Chemokines & Growth Factors
Reconstitution
It is recommended to reconstitute the lyophilized recombinant human Interleukin-2 (IL-2) in sterile 18 Momega-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Storage
Lyophilized, recombinant human Interleukin-2 (IL-2), remains stable at room temperature for three weeks, but it is best stored desiccated below -18C. Upon reconstitution recombinant human Interleukin-2 (IL-2) should be stored at 4C for up to seven days. For long term storage it is recommended that a carrier protein (0.1% HSA or BSA) be added. Avoid repeated freeze-thaw cycles.
Manufacturers Category
Proteins
Manufacturers Product Line
Cytokines
Product Origin
USA

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 ug
Available: In stock
available

Delivery expected until 4/18/2024 

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