Manufacturer |
GenScript
|
Category |
|
Type |
Proteins |
Specific against |
Human |
Amount |
1 mg |
Item no. |
Z00377-1 |
Targets |
IL15, CD25, CD24, IL2 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Available |
|
Specificity |
The ED50 as determined by the dose-dependant stimulation of the proliferation of CTLL-2 was found to be <0.5 ng/ml, corresponding to a Specific Activity of 2x106 IU/mg. |
Description |
Interleukin 15 (IL-15), is a cytokine that possesses a variety of biological functions. Interleukin 15 (IL-15) stimulates the proliferation of T-lymphocytes, which requires interaction of IL-15 with components of IL-2R, including IL-2R and probably IL-2R gamma, but not IL-2R. Recombinant human Interleukin 15 (IL-15), produced in, E. coli, is a single, non-glycosylated polypeptide chain containing 114 amino acids and having a molecular mass of 12, 774 Da. |
Endotoxin Level |
Less than 0.1 ng/ug (1 EU/ug) of recombinant human Interleukin-15 (IL-15) as determined by LAL test. |
Formulation |
Recombinant human Interleukin-15 (IL-15), was lyophilized after extensive dialysis against 20mM PB, pH7.5, 150mM NaCl buffer. |
M.W. |
12, 774 Da |
Product Line |
Cytokine, Chemokines & Growth Factors |
Reconstitution |
It is recommended to reconstitute the lyophilized, Recombinant Human Interleukin 15 (IL-15), in sterile 18 Momega-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. |
Storage |
Lyophilized, recombinant human Interleukin 15 (IL-15), remains stable at room temperature for three weeks, but it is best stored desiccated below -18C. Upon reconstitution recombinant human Interleukin 15 (IL-15) should be stored at 4C for up to seven days. For long term storage it is recommended that a carrier protein (0.1% HSA or BSA ) be added. Avoid repeated freeze-thaw cycles. |
Manufacturers Category |
Proteins |
Manufacturers Product Line |
Cytokines |
Product Origin |
USA |
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