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NRG-1β2, Human

NRG-1β2, Human

Manufacturer	GenScript
Category	Oncology Infectious Diseases Viral Infections Coronavirus (COVID-19) Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Proliferation By Organ Lung Cancer Breast Cancer
Type	Proteins
Specific against	Human
Format	Sterile Filtered White lyophilized (freeze-dried) powder.
Amount	50 ug
Item no.	Z02747-50
eClass 6.1	34160400
eClass 9.0	42020190
Available
Specificity	Fully biologically active when compared to standard. The ED50 determined by a cell proliferation assay using serum free human MCF-7 cells is less than 83 ng/ml, corresponding to a specific activity of 1.2 x 104 IU/mg.
Description	Neuregulin is a signaling protein for ErbB2/ErbB4 receptor heterodimers on the cardiac muscle cells, playing an important role in heart structure and function through inducing ErbB2/ErbB4 receptor phosphorylation and cardiomyocyte differentiation. Research on molecular level discovered that recombinant neuregulin could make disturbed myocardial cell structure into order and strengthen the connection between myocardial cells by intercalated discs re-organization.
Endotoxin Level	Less than 0.2EU/ug of rHuNRG-1 as determined by LAL method.
Formulation	Lyophilized from a 0.2um filtered, concentrated, solution, in PBS, pH 7.4.
M.W.	Approximately 7.0 kDa, a single non-glycosylated polypeptide chain containing 61 amino acids.
Product Line	Cytokine, Chemokines & Growth Factors
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 C. Further dilutions should be made in appropriate buffered solutions.
Storage	This lyophilized preparation is stable at 2-8 C, but should be kept at -20 C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 C to -70 C. Avoid repeated freeze/thaw cycles.
Usage	This material is for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.
Manufacturers Category	Proteins
Manufacturers Product Line	Neurotrophines
Product Origin	USA

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 5/16/2024