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Parathyroid Hormone 1-34 (PTH 1-34aa), Human

Parathyroid Hormone 1-34 (PTH 1-34aa), Human

Manufacturer	GenScript
Category	Oncology Neuroscience Molecular Targets for Neuroscience Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Necrosis By Organ Thyroid Cancer
Type	Proteins
Specific against	Human
Format	Sterile Filtered White lyophilized (freeze-dried) powder.
Amount	100ug
Item no.	Z02792-100
Targets	CALCA, PTH
eClass 6.1	34160400
eClass 9.0	42020190
Available
Specificity	Fully biologically active when compared to standard. The specific activity is determined by UMR106 cell/cAMP method, corresponding to a specific activity of ＞, 1.0 x 104 IU/mg.
Description	Polypeptide hormones secreted by the parathyroid glands, which promote release of calcium from bone to extracellular fluid by activating osteoblasts and inhibiting osteoclasts, indirectly promote increased intestinal absorption of calcium, and promote renal tubular reabsorption of calcium and increased renal excretion of phosphates. It is a major regulator of bone metabolism. Secretion of parathyroid hormone increases when the level of calcium in the extracellular fluid is low. Its action is opposed by calcitonin.
Endotoxin Level	Less than 0.2EU/ug of rHuPTH1-34 as determined by LAL method.
Formulation	Lyophilized from a 0.2µ, m filtered concentrated, solution in 20mM PB, pH 7.0, containing 4% mannitol.
M.W.	4117.8 Da, a single non-glycosylated polypeptide chain containing 34 amino acids.
Product Line	Cytokine, Chemokines & Growth Factors
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °, C. Further dilutions should be made in appropriate buffered solutions.
Storage	This lyophilized preparation is stable at 2-8 C, but should be kept at -20 C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 C to -70 C. Avoid repeated freeze/thaw cycles.
Usage	This material is for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.
Product Origin	USA

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 5/23/2024