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M-CSF, Human(CHO-expressed)

M-CSF, Human(CHO-expressed)

Item no.	Z02924-50
Manufacturer	GenScript
Amount	50 ug
Quantity options	1 mg 10 ug 50 ug
Category	Oncology By Cell Type Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Peptides & Proteins Recombinant Proteins Cardiovascular Research Hypertension By Organ Breast Cancer Uterine, Ovarian & Cervical Cancer
Type	Proteins
Specific against	Human (Homo sapiens)
Purity	> 95% as analyzed by SDS-PAGE and HPLC.
Sequence	Glu33-Ser190 (Accession # NP_757350).
Citations	1. Fiona J. Pixley and E. Richard Stanley (2004), Trends in Cell Biology, 14: 628. 2. Kauma SW et al. (1991), J Clin Endocrinol Metab, 73(4), 746. 3. Jani R. Jensen et al. (2010), Fertil Steril. 93(1): 251. 4. Baiocchi G et al. (1991), Cancer, 1991, 67:990.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	protein/Z02924_50-Macrophage_Colony_Stimulating_Factor_M_CSF_Human,Human Macrophage-Colony Stimulating Factor (M-CSF), also known as Colony Stimulating Factor-1 (CSF-1), can stimulate the survival, proliferation and differentiation of mononuclear phagocytes, in addition to the spreading and motility of macrophages[1]. M-CSF is mainly produced by monocytes, macrophages, fibroblasts, and endothelial cells[2]. M-CSF interaction with its receptor, c-fms, has been implicated in the growth, invasion, and metastasis of of several diseases, including breast and endometrial cancers, [1][3][4] .</td></tr><tr><th>M.W.</th><td colspan="7"> 32-40 kDa, observed by non-reducing SDS-PAGE.</td></tr><tr><th>Purity</th><td colspan="7"> > 95% as analyzed by SDS-PAGE and HPLC.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> <0.2 EU/ug, determined by LAL method.</td></tr><tr><th>Specific Activity</th><td colspan="7"> ED50, 2×105 units/mg.</td></tr><tr><th>Storage</th><td colspan="7"> Lyophilized recombinant, human Macrophage-Colony Stimulating Factor (rhM-CSF), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rhM-CSF should be stable up to 1 week at 4C or up to 2 months at -20C.</td></tr><tr><th>Formulation</th><td colspan="7"> Lyophilized after extensive dialysis against PBS.</td></tr><tr><th>Reconstitution</th><td colspan="7"> Reconstituted in ddH2O or PBS at 100 ug/ml.</td></tr><tr><th>Sequence</th><td colspan="7"> Glu33-Ser190 (Accession
Similar products	Macrophage
Shipping Condition	Cool pack
Available
Specificity	ED50, 2x105 units/mg.
Manufacturer - Category	Proteins
Country of Origin	USA
Shipping Temperature	4°C
Storage Conditions	-80°C
Molecular Weight	32-40 kDa, observed by non-reducing SDS-PAGE.
Product Line	Growth Factors
Manufacturer - Specificity	ED50, 2x105 units/mg.
Description	Human Macrophage-Colony Stimulating Factor (M-CSF), also known as Colony Stimulating Factor-1 (CSF-1), can stimulate the survival, proliferation and differentiation of mononuclear phagocytes, in addition to the spreading and motility of macrophages[1]. M-CSF is mainly produced by monocytes, macrophages, fibroblasts, and endothelial cells[2]. M-CSF interaction with its receptor, c-fms, has been implicated in the growth, invasion, and metastasis of of several diseases, including breast and endometrial cancers, [1][3][4] .
Reconstitution	Reconstituted in ddH2O or PBS at 100 ug/ml.
Formulation	Lyophilized after extensive dialysis against PBS.
Endotoxin Level	<0.2 EU/ug, determined by LAL method.
Notes	For research use only

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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