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Fibrobalst Growth Factor-13 (FGF-13), Human

Fibrobalst Growth Factor-13 (FGF-13), Human

Item no.	Z02936-5
Manufacturer	GenScript
Amount	5 ug
Quantity options	1 mg 20 ug 5 ug
Category	Oncology Neuroscience Neural Lineage Markers By Cell Type Carcinoma Hematology Myeloma Peptides & Proteins Recombinant Proteins Cardiovascular Research Ischemia & Reperfusion Injury
Type	Proteins
Format	Sterile Filtered White lyophilized (freeze-dried) powder.
Specific against	Human (Homo sapiens)
Purity	>95% by SDS-PAGE and HPLC analyses.
Sequence	MAAAIASSLI RQKRQARERE KSNACKCVSS PSKGKTSCDK NKLNVFSRVK LFGSKKRRRR RPEPQLKGIV TKLYSRQGYH LQLQADGTID GTKDEDSTYT LFNLIPVGLR VVAIQGVQTK LYLAMNSEGY LYTSELFTPE CKFKESVFEN YYVTYSSMIY RQQQSGRGWY LGLNKEGEIM KGNHVKKNKP AAHFLPKPLK VAMYKEPSLH DLTEFSRSGS GTPTKSRSVS GV
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	protein/Z02936_5-Fibrobalst_Growth_Factor_13_FGF_13_Human, Fibroblast growth factor 13 (FGF13) is a new member of the fibroblast growth factor (FGF) family. They possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. FGF-13 was initially identified as FHF2 along with three other FHF factors, FHF1/FGF12, FHF3/FGF-11 and FHF4/FGF14 that comprise a unique intracellular FGF (iFGF) subfamily expressed throughout the developing and adult nervous system. Human FGF13 stimulated the phenotypic differentiation of cortical neurons. FGF13 interacts with voltage-gated sodium channel alpha subunit, and colocalizes at the nodes of Ranvier of dorsal root axons. The mechanism of action for FGF13 in neural development has not been described in detail. </td></tr><tr><th>M.W.</th><td colspan="7"> Approximately 27.6 kDa, a single non-glycosylated polypeptide chain containing 245 amino acids.</td></tr><tr><th>Purity</th><td colspan="7"> >95% by SDS-PAGE and HPLC analyses.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> Less than 1EU/ug of rHuFGF-13 as determined by LAL method.</td></tr><tr><th>Storage</th><td colspan="7"> This lyophilized preparation is stable at 2-8C, but should be kept at -20C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20C to -70C. Avoid repeated freeze/thaw cycles. </td></tr><tr><th>Formulation</th><td colspan="7"> Lyophilized from a 0.2 um filtered concentrated solution in 20mM Tris, pH 8.5, 500mM NaCl.</td></tr><tr><th>Reconstitution</th><td colspan="7"> We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at <=-20C. Further dilutions should be made in appropriate buffered solutions.</td></tr><tr><th>Physical Appearance</th><td colspan="7"> Sterile Filtered White lyophilized (freeze-dried) powder.</td></tr><tr><th>Sequence</th><td colspan="7"> MAAAIASSLI RQKRQARERE KSNACKCVSS PSKGKTSCDK NKLNVFSRVK LFGSKKRRRR RPEPQLKGIV TKLYSRQGYH LQLQADGTID GTKDEDSTYT LFNLIPVGLR VVAIQGVQTK LYLAMNSEGY LYTSELFTPE CKFKESVFEN YYVTYSSMIY RQQQSGRGWY LGLNKEGEIM KGNHVKKNKP AAHFLPKPLK VAMYKEPSLH DLTEFSRSGS GTPTKSRSVS GVLNGGKSMS HNEST</td></tr>
Similar products	Fibrobalst
Available
Country of Origin	USA
Storage Conditions	This lyophilized preparation is stable at 2-8C, but should be kept at -20C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20C to -70C. Avoid repeated freeze/thaw cycles.
Molecular Weight	Approximately 27.6 kDa, a single non-glycosylated polypeptide chain containing 245 amino acids.
Product Line	Cytokine, Chemokines & Growth Factors
Description	Fibroblast growth factor 13 (FGF13) is a new member of the fibroblast growth factor (FGF) family. They possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. FGF-13 was initially identified as FHF2 along with three other FHF factors, FHF1/FGF12, FHF3/FGF-11 and FHF4/FGF14 that comprise a unique intracellular FGF (iFGF) subfamily expressed throughout the developing and adult nervous system. Human FGF13 stimulated the phenotypic differentiation of cortical neurons. FGF13 interacts with voltage-gated sodium channel alpha subunit, and colocalizes at the nodes of Ranvier of dorsal root axons. The mechanism of action for FGF13 in neural development has not been described in detail.
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at <=-20C. Further dilutions should be made in appropriate buffered solutions.
Formulation	Lyophilized from a 0.2 um filtered concentrated solution in 20mM Tris, pH 8.5, 500mM NaCl.
Endotoxin Level	Less than 1EU/ug of rHuFGF-13 as determined by LAL method.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5 ug

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Delivery expected until 9/25/2025

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