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UBE2B/HR6B, His, Human

UBE2B/HR6B, His, Human

Manufacturer	GenScript
Category	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Neural Signaling Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Autophagy
Type	Proteins
Specific against	Human
Format	Sterile Filtered White lyophilized (freeze-dried) powder.
Amount	50ug
Item no.	Z02967-50
Targets	ACHE, SST
eClass 6.1	34160400
eClass 9.0	42020190
Available
Description	This E2 enzyme encodes for the human homolog of the yeast DNA repair gene RAD6, which is induced by DNA damaging agents. UBE2B can conjugate ubiquitin to histone H2A in an E3- independent manner in vitro, and is essential for the multi-ubiquitination and degradation of N-end rule substrates. Additionally, UBE2B may have a role in sepsis-induced muscle protein proteolysis and cancer-induced cachexia.
Endotoxin Level	Less than 1EU/ug of rHuUBE2B, His as determined by LAL method.
Formulation	Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
M.W.	Approximately 19.0 kDa, a single non-glycosylated polypeptide chain containing 152 amino acids (a.a.) of human UBE2B and 14 a.a. vector sequence including 6 x His tag at N-terminus.
Product Line	Others
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at <-20C. Further dilutions should be made in appropriate buffered solutions.
Storage	This lyophilized preparation is stable at 2-8C, but should be kept at -20C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20C to -70C. Avoid repeated freeze/thaw cycles.
Product Origin	USA

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ug

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Delivery expected until 5/16/2024