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Comparison

FGF-4, Human European Partner

Item no. Z02984-25
Manufacturer GenScript
Amount 25 ug
Quantity options 100 ug 25 ug 5 ug
Category
Type Proteins
Specific against Human (Homo sapiens)
Purity > 95% by SDS-PAGE and HPLC analyses.
Sequence Ala31-Leu206 (accession number:P08620), expressed with an N-terminal Met.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias protein/Z02984_25-Fibroblast_Growth_Factor_4_FGF_4_Human,Fibroblast Growth Factor-4 (FGF-4), also known as K-FGF is a heparin-binding growth factor of the FGF family.It was identified by its oncogenic transforming activity. FGF-4 and FGF-3 are located closely on chromosome 11. FGF-4 and its receptors (FGF R1c, 2c, 3c and 4) play an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. FGF-4 is required for normal limb and cardiac valve development during embryogenesis. Recombinant, human Fibroblast Growth Factor-4 (rhFGF-4), produced in, E. coli, is a single non-glycosylated polypeptide chain containing 177 amino acids. A fully biologically active molecule obtained by proprietary chromatographic techniques at GenScript, rhFGF-4 has a molecular mass of 19.4kDa as analyzed by reducing SDS-PAGE.</td></tr><tr><th>M.W.</th><td colspan="7"> 19.4kDa, observed by reducing SDS-PAGE.</td></tr><tr><th>Purity</th><td colspan="7"> > 95% by SDS-PAGE and HPLC analyses.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> <0.2 EU/ug, determined by LAL method.</td></tr><tr><th>Specific Activity</th><td colspan="7"> ED50 2.0× 106 units/mg.</td></tr><tr><th>Storage</th><td colspan="7"> Lyophilized recombinant, human Fibroblast Growth Factor-4 (rhFGF-4), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rhFGF-4 should be stable up to 2 weeks at 4C or up to 3 months at -20C.</td></tr><tr><th>Formulation</th><td colspan="7"> Lyophilized after extensive dialysis against 50mM HEPES, 750mM NaCl, pH7.5.</td></tr><tr><th>Reconstitution</th><td colspan="7"> Reconstituted in ddH2O at 100 ug/ml.</td></tr><tr><th>Sequence</th><td colspan="7"> Ala31-Leu206 (accession number:P08620), expressed with an N-terminal Met.</td></tr><tr><th>Note</th><td colspan="7"> For research use only</td></tr>
Similar products Fibroblast
Shipping condition Cool pack
Available
Specificity ED50 2.0x 106 units/mg.
Manufacturer - Category
Proteins
Country of Origin
USA
Shipping Temperature
4°C
Storage Conditions
-80°C
Molecular Weight
19.4kDa, observed by reducing SDS-PAGE.
Product Line
Growth Factors
Manufacturer - Specificity
ED50 2.0x 106 units/mg.
Description
Fibroblast Growth Factor-4 (FGF-4), also known as K-FGF is a heparin-binding growth factor of the FGF family.It was identified by its oncogenic transforming activity. FGF-4 and FGF-3 are located closely on chromosome 11. FGF-4 and its receptors (FGF R1c, 2c, 3c and 4) play an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. FGF-4 is required for normal limb and cardiac valve development during embryogenesis. Recombinant, human Fibroblast Growth Factor-4 (rhFGF-4), produced in, E. coli, is a single non-glycosylated polypeptide chain containing 177 amino acids. A fully biologically active molecule obtained by proprietary chromatographic techniques at GenScript, rhFGF-4 has a molecular mass of 19.4kDa as analyzed by reducing SDS-PAGE.
Reconstitution
Reconstituted in ddH2O at 100 ug/ml.
Formulation
Lyophilized after extensive dialysis against 50mM HEPES, 750mM NaCl, pH7.5.
Endotoxin Level
<0.2 EU/ug, determined by LAL method.
Notes
For research use only

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Z02984-25-datasheet.pdf

Amount: 25 ug
Available: In stock
available

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