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IL-3, Human(CHO-expressed)

IL-3, Human(CHO-expressed)

Item no.	Z02991-50
Manufacturer	GenScript
Amount	50 ug
Quantity options	1 mg 10 ug 50 ug
Category	Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Cardiovascular Research Toxicity & Cytotoxicity Hypertension
Type	Proteins
Specific against	Human (Homo sapiens)
Purity	> 95% as analyzed by SDS-PAGE and HPLC.
Sequence	Ala20-Phe152 (Accession # Q6GS87).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	protein/Z02991_50-Interleukin_3_IL_3_Human,Interleukin-3 (IL-3), is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant human interleukin 3, expressed in, CHO, cells is glycosylated protein with molecular weight range from 17 to 30 kDa shown in non-reducing SDS-PAGE.</td></tr><tr><th>M.W.</th><td colspan="7"> 17-30 kDa, observed by non-reducing SDS-PAGE.</td></tr><tr><th>Purity</th><td colspan="7"> > 95% as analyzed by SDS-PAGE and HPLC.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> < 0.2 EU/ug, determined by LAL method.</td></tr><tr><th>Specific Activity</th><td colspan="7"> ED50, 1×107 units/mg.</td></tr><tr><th>Storage</th><td colspan="7"> Lyophilized recombinant, human Interlerkin 3 (IL-3), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rhIL-3 should be stable up to 1 week at 4C or up to 2 months at -20C.</td></tr><tr><th>Formulation</th><td colspan="7"> Lyophilized after extensive dialysis against PBS.</td></tr><tr><th>Reconstitution</th><td colspan="7"> Reconstituted in ddH2O or PBS at 100 ug/ml.</td></tr><tr><th>Sequence</th><td colspan="7"> Ala20-Phe152 (Accession
Similar products	Interleukin
Shipping Condition	Cool pack
Available
Specificity	ED50, 1x107 units/mg.
Manufacturer - Category	Proteins
Country of Origin	USA
Shipping Temperature	4°C
Storage Conditions	-80°C
Molecular Weight	17-30 kDa, observed by non-reducing SDS-PAGE.
Product Line	Cytokines
Manufacturer - Specificity	ED50, 1x107 units/mg.
Description	Interleukin-3 (IL-3), is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant human interleukin 3, expressed in, CHO, cells is glycosylated protein with molecular weight range from 17 to 30 kDa shown in non-reducing SDS-PAGE.
Reconstitution	Reconstituted in ddH2O or PBS at 100 ug/ml.
Formulation	Lyophilized after extensive dialysis against PBS.
Endotoxin Level	< 0.2 EU/ug, determined by LAL method.
Notes	For research use only

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Z02991-50.pdf

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Amount: 50 ug

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Delivery expected until 9/11/2025

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