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IFN-α 2b, Human

IFN-α 2b, Human

Item no.	Z03002-10
Manufacturer	GenScript
Amount	10 ug
Quantity options	1 mg 10 ug 50 ug
Category	Oncology Peptides & Proteins Recombinant Proteins By Organ Pancreatic Cancer
Type	Proteins
Specific against	Human (Homo sapiens)
Purity	> 95% by SDS-PAGE and HPLC analyses.
Sequence	Cys24-Glu188(Lys46Arg) (accession number: P01563).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	protein/Z03002_10-Interferon_Alpha_2b_IFN_Alpha_2b_Human,Interferon-Alpha 2b (IFN-Alpha 2b), produced by leukocytes is a member of Interferon family. IFN-alpha is mainly involved in innate immune response against a broad range of viral infections. IFN-alpha 2 has three acid stable forms (a,b,c) signaling through IFNAR2. IFN-alpha 2b shares 99.4% aa sequence identity with both IFN-alpha 2a and 2c. IFN-alpha contains four highly conserved cysteine residues which form two disulfide bonds, one of which is necessary for biological activity. Recombinant, human Interferon-Alpha 2b (rhIFN-Alpha 2b), produced in, E.coli, is a single non-glycosylated polypeptide chain containing 165 amino acids. A fully biologically active molecule, rhIFN-Alpha 2b has a molecular mass of 19.2kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.</td></tr><tr><th>M.W.</th><td colspan="7"> 19.2kDa, observed by reducing SDS-PAGE.</td></tr><tr><th>Purity</th><td colspan="7">> 95% by SDS-PAGE and HPLC analyses.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> < 0.2 EU/ug, determined by LAL method.</td></tr><tr><th>Specific Activity</th><td colspan="7"> ED50, 2.0× 107 units/mg.</td></tr><tr><th>Storage</th><td colspan="7"> Lyophilized recombinant, human Interferon-Alpha 2b (rhIFN-Alpha 2b), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rhIFN-Alpha 2b should be stable up to 2 weeks at 4C or up to 3 months at -20C.</td></tr><tr><th>Formulation</th><td colspan="7"> Lyophilized after extensive dialysis against PBS.</td></tr><tr><th>Reconstitution</th><td colspan="7"> Reconstituted in ddH2O at 100 ug/ml.</td></tr><tr><th>Sequence</th><td colspan="7"> Cys24-Glu188(Lys46Arg) (accession number: P01563).</td></tr><tr><th>Note</th><td colspan="7"> For research use only</td></tr>
Similar products	Interferon-Alpha
Shipping Condition	Cool pack
Available
Specificity	ED50, 2.0x 107 units/mg.
Manufacturer - Category	Proteins
Country of Origin	USA
Shipping Temperature	4°C
Storage Conditions	-80°C
Molecular Weight	19.2kDa, observed by reducing SDS-PAGE.
Product Line	Cytokines
Manufacturer - Specificity	ED50, 2.0x 107 units/mg.
Description	Interferon-Alpha 2b (IFN-Alpha 2b), produced by leukocytes is a member of Interferon family. IFN-alpha is mainly involved in innate immune response against a broad range of viral infections. IFN-alpha 2 has three acid stable forms (a, b, c) signaling through IFNAR2. IFN-alpha 2b shares 99.4% aa sequence identity with both IFN-alpha 2a and 2c. IFN-alpha contains four highly conserved cysteine residues which form two disulfide bonds, one of which is necessary for biological activity. Recombinant, human Interferon-Alpha 2b (rhIFN-Alpha 2b), produced in, E.coli, is a single non-glycosylated polypeptide chain containing 165 amino acids. A fully biologically active molecule, rhIFN-Alpha 2b has a molecular mass of 19.2kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
Reconstitution	Reconstituted in ddH2O at 100 ug/ml.
Formulation	Lyophilized after extensive dialysis against PBS.
Endotoxin Level	< 0.2 EU/ug, determined by LAL method.
Notes	For research use only

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Z03002-10-datasheet.pdf

Z03002-10-safety-datasheet.pdf