Comparison

Shh, Mouse European Partner

Item no. Z02990-50
Manufacturer GenScript
Amount 50 ug
Quantity options 1 mg 10 ug 50 ug
Category
Type Proteins
Specific against Mouse (Murine, Mus musculus)
Purity > 95% by SDS-PAGE and HPLC analyses.
Sequence Cys25-Gly198 (Cys25Ile-Val-Ile)(accession number:Q62226).
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias protein/Z02990_50-Sonic_Hedgehog_Shh_Mouse,Sonic Hedgehog (Shh), is a member of the Hedgehog (Hh) family of highly conserved proteins which are widely represented throughout the animal kingdom. In mammal, there are threerelatedHh proteins, Sonic (Shh), Desert (Dhh) and Indian (Ihh). They share a high degree of amino-acid sequence identity (e.g. Shh and Ihh are 93% identical). Sonic Hedgehog plays a role in cell growth, cell specialization, and the normal shaping (patterning) of the body. Shh is also important for development of the brain and spinal cord (central nervous system), eyes, limbs, and many other parts of the body. Recombinant, mouseSonic Hedgehog(rmShh), produced in, E.coli, is a single non-glycosylated polypeptide chain containing 176 amino acids. A fully biologically active molecule, rmShh,is obtained by proprietary chromatographic techniques at GenScript with a molecular mass of 19.8kDa analyzed by reducing SDS-PAGE.</td></tr><tr><th>M.W.</th><td colspan="7"> 19.8kDa, observed by reducing SDS-PAGE.</td></tr><tr><th>Purity</th><td colspan="7"> > 95% by SDS-PAGE and HPLC analyses.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> <0.2 EU/ug, determined by LAL method.</td></tr><tr><th>Specific Activity</th><td colspan="7"> ED50 1.0× 103units/mg.</td></tr><tr><th>Storage</th><td colspan="7"> Lyophilized recombinant, mouseSonic Hedgehog(rmShh) remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rmShhshould be stable up to 2 weeks at 4C or up to 3 months at -20C.</td></tr><tr><th>Formulation</th><td colspan="7"> Lyophilized after extensive dialysis against PBS.</td></tr><tr><th>Reconstitution</th><td colspan="7"> Reconstituted in ddH2O at 100 ug/ml.</td></tr><tr><th>Sequence</th><td colspan="7"> Cys25-Gly198 (Cys25Ile-Val-Ile)(accession number:Q62226).</td></tr><tr><th>Note</th><td colspan="7"> For research use only</td></tr>
Similar products Sonic
Shipping Condition Cool pack
Available
Specificity ED50 1.0x 103units/mg.
Manufacturer - Category
Proteins
Country of Origin
USA
Shipping Temperature
4°C
Storage Conditions
-80°C
Molecular Weight
19.8kDa, observed by reducing SDS-PAGE.
Product Line
Cytokines
Manufacturer - Specificity
ED50 1.0x 103units/mg.
Description
Sonic Hedgehog (Shh), is a member of the Hedgehog (Hh) family of highly conserved proteins which are widely represented throughout the animal kingdom. In mammal, there are threerelatedHh proteins, Sonic (Shh), Desert (Dhh) and Indian (Ihh). They share a high degree of amino-acid sequence identity (e.g. Shh and Ihh are 93% identical). Sonic Hedgehog plays a role in cell growth, cell specialization, and the normal shaping (patterning) of the body. Shh is also important for development of the brain and spinal cord (central nervous system), eyes, limbs, and many other parts of the body. Recombinant, mouseSonic Hedgehog(rmShh), produced in, E.coli, is a single non-glycosylated polypeptide chain containing 176 amino acids. A fully biologically active molecule, rmShh, is obtained by proprietary chromatographic techniques at GenScript with a molecular mass of 19.8kDa analyzed by reducing SDS-PAGE.
Reconstitution
Reconstituted in ddH2O at 100 ug/ml.
Formulation
Lyophilized after extensive dialysis against PBS.
Endotoxin Level
<0.2 EU/ug, determined by LAL method.
Notes
For research use only

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
available

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