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IL-5, Mouse

IL-5, Mouse

Item no.	Z02998-500
Manufacturer	GenScript
Amount	500 ug
Quantity options	10 ug 50 ug 500 ug
Category	Oncology Food Safety Histamines Neuroscience Neuroinflammation Metabolism Diabetes Molecular Targets for Neuroscience Aging & Neurological Disorders By Cell Type Hematology Leukemia Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Cell Status Cell Metabolism Oxidative Stress By Organ Heart & Blood Cancer Bone Cancer
Type	Proteins
Specific against	Mouse (Murine, Mus musculus)
Purity	> 95% by SDS-PAGE and HPLC analyses.
Sequence	Met21-Gly133(accession number: P04401).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	protein/Z02998_500-Interleukin_5_IL_5_Mouse,Interleukin-5 (rmIL-5) ,produced by mast cells, T cells and eosinophils, is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors from the bone marrow. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. IL-5 also promotes differentiation of basophils and primes them for histamine and leukotriene release. Recombinant, mouse Interleukin-5 (rmIL-5), produced in, E.coli, is a disulfide-linked homodimer containing two non-glycosylated polypeptide chains of 113 amino acids each. A fully biologically active molecule, rmIL-5 has a molecular mass of 26.2kDa analyzed by non-reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.</td></tr><tr><th>M.W.</th><td colspan="7"> 26.2kDa, observed by non-reducing SDS-PAGE.</td></tr><tr><th>Purity</th><td colspan="7"> > 95% by SDS-PAGE and HPLC analyses.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> < 0.2 EU/ug, determined by LAL method.</td></tr><tr><th>Specific Activity</th><td colspan="7"> ED50, 5.0× 105 units/mg.</td></tr><tr><th>Storage</th><td colspan="7"> Lyophilized recombinant mouse Interleukin-5 (rmIL-5) remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rmIL-5 should be stable up to 2 weeks at 4C or up to 3 months at -20C.</td></tr><tr><th>Formulation</th><td colspan="7"> Lyophilized after extensive dialysis against PBS.</td></tr><tr><th>Reconstitution</th><td colspan="7"> Reconstituted in ddH2O at 100 ug/ml.</td></tr><tr><th>Sequence</th><td colspan="7"> Met21-Gly133(accession number: P04401).</td></tr><tr><th>Note</th><td colspan="7"> For research use only</td></tr>
Similar products	Interleukin-5
Shipping condition	Cool pack
Available
Specificity	ED50, 5.0x 105 units/mg.
Manufacturer - Category	Proteins
Country of Origin	USA
Shipping Temperature	4°C
Storage Conditions	-80°C
Molecular Weight	26.2kDa, observed by non-reducing SDS-PAGE.
Product Line	Cytokines
Manufacturer - Specificity	ED50, 5.0x 105 units/mg.
Description	Interleukin-5 (rmIL-5) , produced by mast cells, T cells and eosinophils, is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors from the bone marrow. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. IL-5 also promotes differentiation of basophils and primes them for histamine and leukotriene release. Recombinant, mouse Interleukin-5 (rmIL-5), produced in, E.coli, is a disulfide-linked homodimer containing two non-glycosylated polypeptide chains of 113 amino acids each. A fully biologically active molecule, rmIL-5 has a molecular mass of 26.2kDa analyzed by non-reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
Reconstitution	Reconstituted in ddH2O at 100 ug/ml.
Formulation	Lyophilized after extensive dialysis against PBS.
Endotoxin Level	< 0.2 EU/ug, determined by LAL method.
Notes	For research use only

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 5/15/2025