Description |
Granulocyte Macrophage Colony Stimulating Factor (GM-CSF), was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine or immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effectors functions of granulocytes, monocytes/macrophages and eosinophils. |
Storage |
Lyophilized recombinant, murine Granulocyte Macrophage Colony Stimulating Factor (GM-CSF), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rmGM-CSF should be stable up to 1 week at 4C or up to 2 months at -20C. |