Manufacturer |
GenScript
|
Category |
|
Type |
Proteins |
Specific against |
Rat |
Format |
Sterile Filtered White lyophilized (freeze-dried) powder. |
Amount |
50ug |
Item no. |
Z02786-50 |
Targets |
FGF2, FGF1 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Available |
|
Specificity |
Fully biologically active when compared to standard. The ED50 determined by a cell proliferation assay using murine NR6R/3T3 cells is less than 0.2 ng/ml, corresponding to a specific activity of >, 5.0 x 106 IU/mg. |
Description |
FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. |
Endotoxin Level |
Less than 0.2EU/ug of rRtbFGF as determined by LAL method. |
Formulation |
Lyophilized from a 0.2µ, m filtered solution in PBS, pH 7.4. |
M.W. |
Approximately 16.3 kDa, a single non-glycosylated polypeptide chain containing 145 amino acids. |
Product Line |
Cytokine, Chemokines & Growth Factors |
Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °, C. Further dilutions should be made in appropriate buffered solutions. |
Storage |
This lyophilized preparation is stable at 2-8 C, but should be kept at -20 C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 C to -70 C. Avoid repeated freeze/thaw cycles. |
Usage |
This material is for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. |
Product Origin |
USA |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.