Item no. |
Z02982-1 |
Manufacturer |
GenScript
|
Amount |
1 mg |
Quantity options |
1 mg
10 ug
50 ug
|
Category |
|
Type |
Proteins |
Specific against |
Rat (Rattus norvegicus) |
Purity |
> 95% as analyzed by SDS-PAGE and HPLC. |
Sequence |
Glu23-Cys156 (Accession # P01581). |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
protein/Z02982_1-Interferon_gamma_IFN_gamma_Rat,Interferon-gamma (IFN-gamma), also known as Type II interferon or immune interferon, is a cytokine produced primarily by T-lymphocytes and natural killer cells. The active form of IFN-gamma is an antiparallel dimer that interacts with the receptor IFN-gammaR1 and sets off IFN-gamma/JAK/STAT pathway. IFN-gamma signaling does diverse biological functions primarily related to host defense and immune regulation, including antiviral and antibacterial defense, apoptosis, inflammation, and innate and acquired immunity. While IFN-gamma–induced inflammatory cascade summons a variety of immune-related cell types, such as macrophages, natural killer (NK) cells and cytotoxic T lymphocytes (CTLs), IFN-gamma is also implicated in resistance to NK cell and CTL responses and in immune escape in a variety of cancers.</td></tr><tr><th>M.W.</th><td colspan="7"> 15-25 kDa, observed by non-reducing SDS-PAGE.</td></tr><tr><th>Purity</th><td colspan="7"> > 95% as analyzed by SDS-PAGE and HPLC.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> < 0.2 EU/ug, determined by LAL method.</td></tr><tr><th>Specific Activity</th><td colspan="7"> ED50, 4×105 units/mg.</td></tr><tr><th>Storage</th><td colspan="7"> Lyophilized recombinant, Rat Interferon gamma (IFN-gamma), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rrIFN-gamma should be stable up to 1 week at 4C or up to 2 months at -20C.</td></tr><tr><th>Formulation</th><td colspan="7"> Lyophilized after extensive dialysis against PBS.</td></tr><tr><th>Reconstitution</th><td colspan="7"> Reconstituted in ddH2O or PBS at 100 ug/ml.</td></tr><tr><th>Sequence</th><td colspan="7"> Glu23-Cys156 (Accession |
Similar products |
Interferon-gamma |
Shipping condition |
Cool pack |
Available |
|
Specificity |
ED50, 4x105 units/mg. |
Manufacturer - Category |
Proteins |
Country of Origin |
USA |
Shipping Temperature |
4°C |
Storage Conditions |
-80°C |
Molecular Weight |
15-25 kDa, observed by non-reducing SDS-PAGE. |
Product Line |
Cytokines |
Manufacturer - Specificity |
ED50, 4x105 units/mg. |
Description |
Interferon-gamma (IFN-gamma), also known as Type II interferon or immune interferon, is a cytokine produced primarily by T-lymphocytes and natural killer cells. The active form of IFN-gamma is an antiparallel dimer that interacts with the receptor IFN-gammaR1 and sets off IFN-gamma/JAK/STAT pathway. IFN-gamma signaling does diverse biological functions primarily related to host defense and immune regulation, including antiviral and antibacterial defense, apoptosis, inflammation, and innate and acquired immunity. While IFN-gamma–induced inflammatory cascade summons a variety of immune-related cell types, such as macrophages, natural killer (NK) cells and cytotoxic T lymphocytes (CTLs), IFN-gamma is also implicated in resistance to NK cell and CTL responses and in immune escape in a variety of cancers. |
Reconstitution |
Reconstituted in ddH2O or PBS at 100 ug/ml. |
Formulation |
Lyophilized after extensive dialysis against PBS. |
Endotoxin Level |
< 0.2 EU/ug, determined by LAL method. |
Notes |
For research use only |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.