MOUSE ANTI HUMAN CD5:FITC

CD5

Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

May act as a receptor in regulating T-cell proliferation. CD5 interacts with CD72/LYB-2. Subcellular locationMembrane; Single-pass type I membrane protein. Sequence similaritiesContains 3 SRCR domains. 1. Soell M et al. (1995) Activation of human monocytes by streptococcal rhamnose glucose polymers is mediated by CD14 antigen and mannan binding protein inhibits TNF-alpha release. J. Immunol. 154: 851-860. 2. Gupta V. K. et al. (1996) Identification of the sheep homologue of the monocyte cell surface molecule--CD14. Vet Immunol. Immunopathol. 51: 89-99. 3. Sopp P. et al. (1997) Cross-reactivity of monoclonal antibodies to defined human leucocyte differentiation antigens with bovine cells. Vet. Immunol. Immunopathol. 56: 11-25. 4. Willett B. et al. (2003) Expression of CXCR4 on feline peripheral blood mononuclear cells: effect of feline immunodeficiency virus infection. J. Virol. 77: 709 - 712. 5. Werling D et al. (1998) Analysis of the phenotype and phagocytic activity of monocytes/macrophages from cattle infected with the bovine leukaemia virus. Vet. Immunol. Immunopathol. 62:185-195. 6. Yang H. et al. (2003) Antibody to CD14 like CXCR4-specific antibody 12G5 could inhibit CXCR4-dependent chemotaxis and HIV Env-mediated cell fusion. Immunol. Letters 88: 27-30. 7. Yoshino N. et al. (2000) Upgrading of flow cytometric analysis for absolute counts cytokines and other antigenic molecules of Cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies. Exp. Anim. 49 (2): 97-110. 8. Jacobsen C. N. et al. (1993) Reactivities of 20 anti-human monoclonal antibodies with leucocytes from ten different animal species. Vet. Immunol. Immunopathol. 39: 461-466. 9. Martel C. J. & Aasted B. (2009) Characterization of antibodies against ferret immunoglobulins cytokines and CD markers. Vet Immunol Immunopathol. 132:109-15. [1] \" The monocyte differentiation antigen CD14 is anchored to the cell membrane by a phosphatidylinositol linkage. \" Haziot A. Chen S. Ferrero E. Low M. G. Silber R. Goyert S. M. J. Immunol. 141:547-552(1988) [PubMed: 3385210] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA]. [2] \" Nucleotide sequence of the gene encoding the monocyte differentiation antigen CD14. \" Ferrero E. Goyert S. M. Nucleic Acids Res. 16:4173-4173(1988) [PubMed: 2453848] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Tissue: Lymphocyte. [3] \" Mouse and human CD14 (myeloid cell-specific leucine-rich glycoprotein) primary structure deduced from cDNA clones. \" Setoguchi M. Nasu N. Yoshida S. Higuchi Y. Akizuki S. Yamamoto S. Biochim. Biophys. Acta 1008:213-222(1989) [PubMed: 2472171] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Macrophage. [4] \" Monocyte antigen CD14 is a phospholipid anchored membrane protein. \" Simmons D. L. Tan S. Tenen D. G. Nicholson-Weller A. Seed B. Blood 73:284-289(1989) [PubMed: 2462937] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA]. [5] \" Cloning and sequencing of human CD14 gene. \" Long J. Y. Xue Y. N. Sun L. Wang H. X. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Jin Zhan 25:377-378(1998)Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Promyelocytic leukemia. [6] \" Natural selection in the TLR-related genes in the course of primate evolution. \" Nakajima T. Ohtani H. Satta Y. Uno Y. Akari H. Ishida T. Kimura A. Immunogenetics 60:727-735(2008) [PubMed: 18810425] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA]. [7] \" Cloning of human full-length CDSs in BD Creator(TM) system donor vector. \" Kalnine N. Chen X. Rolfs A. Halleck A. Hines L. Eisenstein S. Koundinya M. Raphael J. Moreira D. Kelley T. LaBaer J. Lin Y. Phelan M. Farmer A. Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databasesCited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. [8] Mural R. J. Istrail S. Sutton G. G. Florea L. Halpern A. L. Mobarry C. M. Lippert R. Walenz B. Shatkay H. Dew I. Miller J. R. Flanigan M. J. Edwards N. J. Bolanos R. Fasulo D. Halldorsson B. V. Hannenhalli S. Turner R. Yooseph S. Lu F. Nusskern D. R. Shue B. C. Zheng X. H. Zhong F. Delcher A. L. Huson D. H. Kravitz S. A. Mouchard L. Reinert K. Remington K. A. Clark A. G. Waterman M. S. Eichler E. E. Adams M. D. Hunkapiller M. W. Myers E. W. Venter J. C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databasesCited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. [9] \" The status quality and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). \" The MGC Project TeamGenome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain. [10] \" Expression and secretion of CD14 in glial neoplasms of the brain. \" Deininger M. H. Meyermann R. Schluesener H. J. Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databasesCited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-125. Tissue: Glioblastoma.