Comparison

RAT ANTI MOUSE CD25:FITC

Manufacturer GENWAY
Category
Type Antibody
Specific against Mouse
Amount 0.1 mg
Host Rat
Item no. 20-783-314558
eClass 6.1 32160702
eClass 9.0 32160702
Available
Genway ID:
GWB-1E0C2C
Specificity:
CD25
Isotype:
IgG1
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Preservative Stabilisers:
0. 09% Sodium Azide (NaN3) 1% Bovine Serum AlbuminApprox. Protein Concentrations: IgG concentration 0. 1mg/ml
Immunogen:
B6. 1 CTL cell line
Specificity:
Reacts with the low affinity alpha chain of the interleukin-2 receptor present on activated T and B cells in mice. Clone PC61. 5. 3 is reported to inhibit IL-2 binding and IL-2 dependent proliferation. AbD Recommended Negative Controls: RAT IgG1 NEGATIVE CONTROL:FITC
Function:
Receptor for interleukin-2. Subunit structureNon-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer an intermediate affinity monomer (beta subunit) and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. Subcellular locationMembrane; Single-pass type I membrane protein. Sequence similaritiesContains 2 Sushi (CCP/SCR) domains. 1. Martinon F. et al (2004) Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases. Cell 117:561-74. 2. Zhivotovsky B. et al (2005) Caspase-2 function in response to DNA damage. Biochim. Biophys. Res. Comm. 331:859-67. 3. Wolf B. B. et al (1999) Suicidal tendencies: apoptotic cell death by caspase family proteinases. J. Biol. Chem. 274:20049-52. 4. Fernandes-Alnemri T. et al (1995) Mch2 a new member of the apoptotic Ced-3/Ice cysteine protease gene family. Cancer Res. 55:2737-42. [1] \" Mch2 a new member of the apoptotic Ced-3/Ice cysteine protease gene family. \" Fernandes-Alnemri T. Litwack G. Alnemri E. S. Cancer Res. 55:2737-2742(1995) [PubMed: 7796396] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS ALPHA AND BETA). Tissue: T-cell. [2] NIEHS SNPs programSubmitted (MAR-2003) to the EMBL/GenBank/DDBJ databasesCited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] VARIANT SER-182. [3] \" The status quality and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). \" The MGC Project TeamGenome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM ALPHA). Tissue: Lung. [4] \" The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32. \" Srinivasula S. M. Fernandes-Alnemri T. Zangrilli J. Robertson N. Armstrong R. C. Wang L. Trapani J. A. Tomaselli K. J. Litwack G. Alnemri E. S. J. Biol. Chem. 271:27099-27106(1996) [PubMed: 8900201] [Abstract]Cited for: PROTEOLYTIC PROCESSING. Tissue: Lymphocyte. [5] \" Regulation of caspase-6 and FLIP by the AMPK family member ARK5. \" Suzuki A. Kusakai G. Kishimoto A. Shimojo Y. Miyamoto S. Ogura T. Ochiai A. Esumi H. Oncogene 23:7067-7075(2004) [PubMed: 15273717] [Abstract]Cited for: ENZYME REGULATION PHOSPHORYLATION AT SER-257 MUTAGENESIS OF SER-257. [6] Colinge J. Superti-Furga G. Bennett K. L. Submitted (OCT-2008) to UniProtKBCited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.1 mg
Available: In stock
available

Delivery expected until 4/25/2024 

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