KCNK10 (potassium channel. subfamily K. member 10)

GWB-DFF85C

1:62500

Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. KCNK10 is one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is highly expressed in the kidney and pancreas. This channel is an open rectifier which primarily passes outward

Membrane; Multi-pass membrane protein (Potential).

Belongs to the two pore domain potassium channel (TC 1. A. 1. 8) family [view classification]. Summary: This protein is one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is highly expressed in the kidney and pancreas. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. The protein is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching intracellular acidification and general anaesthetics. Three transcript variants have been identified for this gene. Gu. W. . et al. . (2002) J. Physiol. (Lond. ) 539 (PT 3). 657-668.