Steroid hormone receptor ERR2

Ligand-binding domain of human. Synthetic peptide - KLH conjugated.
Uses: IHC (3 ug/ml) (Optimal dilution to be determined by the researcher)

Nucleus (Potential).

Contains 1 nuclear receptor DNA-binding domain. Summary: This protein is a protein with similarity to the estrogen receptor. Its function is unknown; however a similar protein in mouse plays an essential role in placental development. [1] Zhou W. Liu Z. Wu J. Liu J. Hyder S. M. Antoniou E. and Lubahn D. B. Identification and Characterization of Two Novel Splicing Isoforms of Human ERR{beta}[2] Cheung C. P. Yu S. Wong K. B. Chan L. W. Lai F. M. Wang X. Suetsugi M. Chen S. and Chan F. L. Expression and functional study of estrogen receptor-related receptors in human prostatic cells and tissues[3] Liu P. Y. Christian R. C. Ruan M. Miller V. M. and Fitzpatrick L. A. et al. Correlating androgen and estrogen steroid receptor expression with coronary calcification and atherosclerosis in men without known coronary artery disease[4] Smith L. H. Coats S. R. Qin H. Petrie M. S. Covington J. W. Su M. Eren M. and Vaughan D. E. Differential and opposing regulation of PAI-1 promoter activity by estrogen receptor alpha and estrogen receptor beta in endothelial cells[5] Verdier-Sevrain S. Yaar M. Cantatore J. Traish A. and Gilchrest B. A. Estradiol induces proliferation of keratinocytes via a receptor mediated mechanism[6] Chen F. Zhang Q. McDonald T. Davidoff M. J. Bailey W. Bai C. Liu Q. Caskey C. T. Identification of two hERR2-related novel nuclear receptors utilizing bioinformatics and inverse PCR. [7] Heilig R. Eckenberg R. Petit J. -L. Fonknechten N. Da Silva C. Cattolico L. Levy M. Barbe V. De Berardinis V. Ureta-Vidal A. et al. The DNA sequence and analysis of human chromosome 14.