IgA


Item no.	18-783-76045
Manufacturer	GENWAY
Amount	1 mg
Category	Oncology Antibodies Immunohistochemistry Western Blot ELISA Secondary Antibodies By Organ Lymphatic System Cancer
Type	Antibody
Applications	WB, IHC, ELISA
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-1B7394
Similar products	18-783-76045
Available
Genway ID:	GWB-1B7394
Specificity:	IgA
Specificity:	IgA
Immunogen:	Purified canine IgA
Specificity Note:	This product recognises canine IgA and shows no cross - reactivity with other canine immunoglobulin classes in immunoelectrophoresis.
Antiserum Preparation:	Antisera to canine IgA were raised by repeated immunisation of goat with highly purified antigen. Purified IgG prepared by affinity chromatography.
Buffer Solution:	Phosphate buffered saline
Preservative Stabilisers:		0. 09%Sodium AzideSuggested
Dilution:	Suggested
Dilution:	Immunohistology - Frozen - 1:200 - 1:500Western Blotting - Reducing conditions
Function:	Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
Subunit:	Monomeric or polymeric.
Ptm:	3-Hydroxykynurenine an oxidized tryptophan metabolite that is common in biological fluids reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.
Disease:	A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1; 14)(q21; q32) that forms a FCRL4-IGHA1 fusion protein.
Similarity:	Contains 3 Ig-like (immunoglobulin-like) domains. 1. Benyacoub. J. et al. (2003) Supplementation of food with Enterococcus faecium (SF68) stimulates immune functions in young dogs. 2. Peters. I. R. et al. (2004) Measurement of immunoglobulin concentrations in the feces of healthy dogs

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mg

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Delivery expected until 10/30/2025

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