Comparison

Cytokeratin 7 (C-term)

Item no. 20-203-420727
Manufacturer GENWAY
Amount 0,1 ml
Category
Type Antibody
Applications WB, FC, IP, ICC
Specific against other
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GWB-32500E
Similar products 20-203-420727
Available
Genway ID:
GWB-32500E
Clone ID:
EP1620Y
Immunogen:
A synthetic peptide corresponding to residues near the C-terminus of human CK-7 was used as an immunogen.
Specificity:
A synthetic peptide corresponding to residues near the C-terminus of human CK-7 was used as an immunogen.
Dilution:
WB: 1:1 000 - 10 000ICC: 1:250 - 500FC: 1:20IP: 1:50. Cytokeratins are cytoplasmic intermediate filament proteins expressed by epithelial cells. Keratin 7 (CK7) is expressed in a wide range of epithelial structures in humans. The expression pattern in mice is similar to the reported human distribution with substantial expression observed in lung bladder mesothelium hair follicle and ductal structures (1). Protein expression levels of CK7 appear significantly higher in chromophobe RCC compared to oncocytoma (p < 0. 001). Studies provide further evidence that CK7 and parvalbumin immunostains may be useful in differentiating oncocytoma from chromophobe RCC in problematic cases (2). Also the pattern of immunohistochemical expression of CK 7 along with CK 20 is commonly used to assess possible primary sites of metastatic carcinomas (3). 1. Smith FJ et al. Biochem Biophys Res Commun. 297(4):818-27 2002. 2. Adley BP et al. Anal Quant Cytol Histol 28(4):228-36 20063. Coons SW et al. Endocr Pathol 16(3):201-10 2005. 4. Manufactured under U. S. Patents No. 5 675 063 and 7 429 487

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0,1 ml
Available: In stock
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