« Back
Home /
CD11a [38]

CD11a [38]

Manufacturer	GENWAY
Category	Antibodies Immunohistochemistry Immunoprecipitation Primary Antibodies
Type	Antibody
Specific against	other
Clone	38
Applications	IP, IHC
Amount	0.1 mg
Item no.	20-272-192634
eClass 6.1	32160702
eClass 9.0	32160702
Available
Genway ID:	GWB-53A325
Clone:	38
Isotype:	IgG2a
Immunogen:	Integrin alpha L-positive cell preparation.
Specificity:	Human CD11a
Positive Control:	Tonsil
Target:	CD11a
Localization:	Cell Membrane and Plasma membrane
Concentration:	1. 0 mg/ml
Purification Note:	From hybridoma culture supernatant Storage
Buffer:	Contains 0. 09% sodium azide as preservative.
Application Note:	For FACS: Use at a dilution of 1:50 - 1:100. For IHC-Fr and IP: Use at an assay dependent dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher. Cellular
Localization:	Cell Membrane and Plasma membrane Integrin alpha L chain interacts with the integrin beta 2 subunit/CD18 to form the alpha-L-beta-2 heterodimer. It is expressed on lymphocytes granulocytes monocytes and macrophages and is upregulated on activated T-cells. Integrin alpha L mediates adhesion of lymphocytes to vascular endothelium.
Function:	Integrin alpha-L/beta-2 is a receptor for ICAM1 ICAM2 ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction cytotoxic T-cell mediated killing and antibody dependent killing by granulocytes and monocytes.
Subunit:	Heterodimer of an alpha and a beta subunit. Alpha-L associates with beta-2.
Subcellular Location:	Membrane; Single-pass type I membrane protein.
Tissue Specificity:	Leukocytes.
Domain:	The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
Similarity:	Belongs to the integrin alpha chain family.
Similarity:	Contains 7 FG-GAP repeats.
Similarity:	Contains 1 VWFA domain.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 0.1 mg

available

Delivery expected until 6/28/2024