Progesterone receptor [1A6]

GWB-3499AB

IgG1

Human

Uterus

From hybridoma culture supernatant Storage

For IHC-Fr and IHC-P: Use at a dilution of 1:20 - 1:60. Not tested in other applications. Optimal concentrations/dilutions should be determined by the researcher. * Immediate fixation in Zamboni\' s fixative recommended. ** This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH6. 0 is recommended for this purpose. Myeloma: Spleen cells from immunised mice were fused with cells of the mouse p3-NS1-Ag4-1 myeloma cell line Studies of progesterone receptor expression may provide supplementary information to the determination of estrogen receptor expression in breast cancer tissues.

Interacts with CUEDC2 SMARD1 and with UNC45A.

Composed of three domains: a modulating N-terminal domain a DNA-binding domain and a C-terminal steroid-binding domain.

Contains 1 nuclear receptor DNA-binding domain.