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C9 (C-terminal)

C9 (C-terminal)

Manufacturer	GENWAY
Category	Oncology Antibodies Primary Antibodies By Organ Skin Cancer
Type	Antibody
Specific against	other
Clone	X197
Amount	0.1 mg
Item no.	20-321-175181
eClass 6.1	32160702
eClass 9.0	32160702
Available
Genway ID:	GWB-B79DBB
Clone:	X197
Applications:	The antibody can be used for immuno assays. flow cytometry and Western blotting. Furthermore the antibody is useful for immunohistology on frozen and paraffin sections and inhibition of C9 binding to C5b-8. Human C9 is a soluble glycoprotein of 61 kD. It is the last component in the assembly of the membrane attack complex (MAC). When the complement is activated on target membranes. multiple copies of C9 bind to the C5b-8 complex and assemble the barrel-shaped pore which causes cell lysis. The conformation of C9 changes from globular to a tubular form. The binding of C9 to C5b-8 plays a key role in the function of C9.
Subunit:	Interacts with PARW and MET (By similarity).
Subcellular Location:	Cytoplasm (Probable).
Similarity:	Belongs to the SPSB family.
Similarity:	Contains 1 B30. 2/SPRY domain.
Similarity:	Contains 1 SOCS box domain. [1] Ansari-Lari M. A. Muzny D. M. Lu J. Lu F. Lilley C. E. Spanos S. Malley T. and Gibbs R. A. A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13[2] Ansari-Lari M. A. Shen Y. Muzny D. M. Lee W. and Gibbs R. A. et al. Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination[3] Ansari-Lari M. A. Muzny D. M. Lu J. Lu F. Lilley C. E. Spanos S. Malley T. and Gibbs R. A. Direct Submission[4] Ansari-Lari M. A. Shen Y. Muzny D. M. Lee W. and Gibbs R. A. et al. Direct Submission[5] Ansari-Lari M. A. Shen Y. Muzny D. M. Lee W. and Gibbs R. A. et al. Direct Submission[6] Ansari-Lari M. A. Shen Y. Muzny D. M. Lee W. Gibbs R. A. Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination. [7] Friedel E. J. Nicholson S. E. Nicola N. A. Kile B. T. Hilton D. J. SOCS box proteins.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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Amount: 0.1 mg

available

Delivery expected until 5/30/2024