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U1 snRNP A/B

U1 snRNP A/B

Manufacturer	GENWAY
Category	Antibodies Immunoprecipitation Western Blot Immunofluorescence Primary Antibodies
Type	Antibody
Specific against	other
Clone	9A9
Applications	WB, IF, IP
Amount	1 ml
Item no.	20-511-240343
eClass 6.1	32160702
eClass 9.0	32160702
Available
Genway ID:	GWB-FE7A8F
Isotype:	IgG1
Clone:	9A9Host Animal: Mouse
Immunogen:	Recombinant beta-galactosidase U2B? fusion protein.
Specificity:	Reacts primarily with the human U1A protein and has minor cross-reactivity with the U2B? protein. contained in the U1 and U2 small nuclear ribonucleoprotein (snRNP) complexes.
Type of Product:	Monoclonal Antibodies to Autoimmune Reagents
Concentration:	Not determinedPreservatives: NaN3
Buffer:	Lyophilized from PBS containing 1% BSAApplications Notes : Immunoprecipitation. Immunofluorescence microscopy (1:5?1:10). Western blot (1:5?1:10). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Warning:	This product contains sodium azide which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0. 1â ??1. 0%. When disposing of this reagent through lead or copper plumbing flush with copious volumes of water to prevent azide build-up in drains. MAb to U1 snRNP A/B. Monoclonal Antibody to U1 small nuclear Ribonucleoprotein (snRNP) A/B
Function:	Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process.
Subunit:	Belongs to the spliceosome where it is associated with snRNP U1. Interacts with SFPQ. Also component of a snRNP-free complex with SFPQ.
Subcellular Location:	Nucleus.
Similarity:	Belongs to the RRM U1 A/B\' \' family.
Similarity:	Contains 2 RRM (RNA recognition motif) domains.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 ml

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Delivery expected until 5/30/2024