CD1b

Manufacturer GENWAY
Category
Type Antibody
Specific against other
Clone MT-101
Applications FC
Amount 0.025 mg
ArtNr 20-783-310051
Available
Genway ID:
GWB-760CD1
Specificity:
CD1bNCBI
Gene ID:
910
Specificity:
CD1b
Clone:
MT-101
Immunogen:
Human thymocytes
Fusion Partner:
Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3. X63 Ag8. 653 myeloma cell line.
Preparation:
Purified IgG prepared from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline
Preservative Stabilisers:
0. 09%Sodium Azide1%Bovine Serum AlbuminSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 106 cells in 100ul. Suggested
Dilution:
Flow Cytometry - Neat
Function:
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
Subunit:
Heterodimer with B2M (beta-2-microglobulin). Interacts with saposin C.
Subcellular Location:
Cell membrane; Single-pass type I membrane protein. Endosome membrane. Lysosome membrane. Note=Subject to intracellular trafficking between the cell membrane endosomes and lysosomes. Localizes to cell surface lipid rafts.
Tissue Specificity:
Expressed on cortical thymocytes on certain T-cell leukemias and in various other tissues.
Miscellaneous:
During protein synthesis and maturation CD1 family members bind endogenous lipids that are replaced by lipid or glycolipid antigens when the proteins are internalized and pass through endosomes or lysosomes before trafficking back to the cell surface. Interaction with saposin C is required for the loading of bacterial lipid antigens onto CD1B in the lysososme.
Similarity:
Contains 1 Ig-like (immunoglobulin-like) domain.
Amount: 0.025 mg
Available: In stock
Listprice: €182.24
Discount: -10.0%
Price: €164.02
You save: €18.22
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