CD226


Manufacturer	GENWAY
Category	Oncology Antibodies Flow Cytometry Immunoprecipitation Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody
Specific against	other
Clone	DX11
Applications	FC, IP
Amount	0.025 mg
Item no.	20-783-310307
eClass 6.1	32160702
eClass 9.0	32160702
Available
Genway ID:	GWB-4DD11E
Specificity:	CD226NCBI
Gene ID:	10666
Specificity:	CD226
Clone:	DX11
Immunogen:	Human cytotoxic T lymphocyte clone
Fusion Partner:	Spleen cells from immunised BALB/c mouse were fused with cells of the Sp2/0 myeloma cell line.
Preparation:	Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:	Phosphate buffered saline pH7. 4
Preservative Stabilisers:		0. 09%Sodium AzideSuggested
Flow Cytometry:	Use 10ul of the suggested working dilution to label 1 x 106 cells in 100ul. Suggested
Dilution:	Flow Cytometry - 1/50 - 1/200
Function:	Receptor involved in intercellular adhesion lymphocyte signaling cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell.
Subunit:	Interacts with PVR and PVRL2.
Subcellular Location:	Membrane; Single-pass type I membrane protein (Potential).
Tissue Specificity:	Expressed by peripheral blood T-lymphocytes.
Ptm:	Phosphorylated.
Similarity:	Contains 2 Ig-like C2-type (immunoglobulin-like) domains. 1. Shibuya. A. et al. (1996) DNAM-1. a novel adhesion molecule involved in the cytolytic function of T lymphocytes. 2. Shibuya. A. et al. (1998) Protein kinase C is involved in the regulation of both signaling and adhesion mediated by DNAX Accessory molecule-1 receptor. 3. Kojima. H. et al. (2003) CD226 mediates platelet and megakaryocytic cell adhesion to vascular endothelial cells.

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Amount: 0.025 mg

available

Delivery expected until 5/30/2024