CD80

CD80NCBI

IgG2a

BCL1 cells expressing CD80

Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Flow Cytometry - 1/10 - 1/50

Interacts with adenovirus subgroup B fiber proteins and acts as a receptor for these viruses.

Expressed on activated B-cells macrophages and dendritic cells.

Contains 1 Ig-like V-type (immunoglobulin-like) domain. 1. Nuriya. S. et al. (1996) The differential role of CD86 and CD80 co-stimulatory molecules in the induction and the effector phases of contact hypersensitivity. 2. Jin. L-P et al. (2004) Adoptive transfer of paternal antigen-hyporesponsive T cells induces maternal tolerance to the allogeneic fetus in abortion-prone matings. 3. Nakajima. A. et al. (1997) Requirement of CD28-CD86 co-stimulation in the interaction between antigen-primed T helper type 2 and B cells. 4. Nozawa. K. et al. (2001) Preferential blockade of CD8+ T cell responses by administration of anti-CD137 ligand monoclonal antibody results in differential effect on development of murine acute and chronic graft-versus-host diseases.