CD279


Manufacturer	GENWAY
Category	Oncology Antibodies Flow Cytometry Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody
Specific against	other
Clone	RMP1-30
Applications	FC
Amount	0.025 mg
Item no.	20-783-310503
eClass 6.1	32160702
eClass 9.0	32160702
Available
Genway ID:	GWB-7EB2AB
Specificity:	CD279
Specificity:	CD279
Clone:	RMP1-30
Immunogen:	PD-1 transferred BHK cells
Fusion Partner:	Spleen cells from immunised Sprague Dawley rats were fused with cells of the P3U1 myeloma cell line.
Preparation:	Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:	Phosphate buffered saline pH7. 4
Preservative Stabilisers:		0. 09%Sodium AzideSuggested
Flow Cytometry:	Use 10ul of the suggested working dilution to label 106 cells in 100ul. Suggested
Dilution:	Flow Cytometry - 1/100 - 1/200
Function:	Possible cell death inducer in association with other factors.
Subunit:	Monomer (By similarity).
Subcellular Location:	Membrane; Single-pass type I membrane protein. Developmental Stage: Induced at programmed cell death.
Disease:	Genetic variation in PDCD1 is associated with susceptibility to systemic lupus erythematosus type 2 (SLEB2) [MIM:605218]. Systemic lupus erythematosus is a chronic inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin joints kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.
Similarity:	Contains 1 Ig-like V-type (immunoglobulin-like) domain. 1. Matsumoto. K. et al. (2004) B7-DC regulates asthmatic response by an IFN-gamma-dependent mechanism.

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Amount: 0.025 mg

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Delivery expected until 5/30/2024