CD172g

Manufacturer GENWAY
Category
Type Antibody
Specific against other
Clone OX119
Applications FC
Amount 25 TESTS
ArtNr 20-783-310611
Available
Genway ID:
GWB-B2C69C
Specificity:
CD172gNCBI
Gene ID:
55423
Specificity:
CD172g
Clone:
OX119
Immunogen:
Purified recombinant SIRPgamma. CD4.
Fusion Partner:
Spleen cells from immunised BALB/c mice were fused with cells of the NS-1 myeloma cell line.
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09% Sodium Azide (NaN3) 1% Bovine Serum Albumin
Reconstitution: Reconstitute in 0. 25 ml disilled waterSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. Suggested
Dilution:
Flow Cytometry - Neat - 1/10
Function:
Probable immunoglobulin-like cell surface receptor. On binding with CD47 mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.
Subunit:
Interacts with CD47.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Detected in liver and at very low levels in brain heart lung pancreas kidney placenta and skeletal muscle. Expressed on CD4+ T-cells CD8+ T-cells CD56-bright natural killer (NK) cells CD20+ cells and all activated NK cells. Mainly present in the paracortical T-cell area of lymph nodes with only sparse positive cells in the mantle and in the germinal center of B-cell follicles. In the thymus primarily expressed in the medulla on mature T lymphocytes that have undergone thymic selection.
Similarity:
Contains 2 Ig-like C1-type (immunoglobulin-like) domains.
Similarity:
Contains 1 Ig-like V-type (immunoglobulin-like) domain. 1. Brooke. G. et al. (2004) Human lymphocytes interact directly with CD47 through a novel member of the signal regulatory protein (SIRP) family.
Amount: 25 TESTS
Available: In stock
Listprice: €212.88
Discount: -10.0%
Price: €191.59
You save: €21.29
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