« Back
Home /
AGGRECAN

AGGRECAN


Item no.	20-783-70530
Manufacturer	GENWAY
Amount	2 ml
Category	Oncology Antibodies Immunohistochemistry Immunoprecipitation ELISA Primary Antibodies By Organ Bladder Cancer
Type	Antibody
Applications	IP, IHC, ELISA
Clone	MA75A95 (HAG
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-DBA7B3
Similar products	20-783-70530
Available
Genway ID:	GWB-DBA7B3
Specificity:	AGGRECANNCBI
Gene ID:	176
Specificity:	AGGRECAN
Clone:	MA75A95 (HAG7E1)
Immunogen:	Human cartilage aggrecan
Fusion Partner:	Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
Specificity Note:	This product recognises human aggrecan a proteoglycan component of cartilage matrix. The antibody reacts with both adult and fetal cartilage matrix in immunohistology.
Preparation:	Tissue Culture Supernatant containing 0. 2M Tris/HCl pH7. 4 and 5-10% foetal calf serum
Preservative Stabilisers:		0. 09%Sodium Azide
Function:	This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.
Subunit:	Interacts with FBLN1 (By similarity).
Subcellular Location:	Secreted extracellular space extracellular matrix (By similarity).
Domain:	Two globular domains G1 and G2 comprise the N-terminus of the proteoglycan while another globular region G3 makes up the C-terminus. G1 contains Link domains and thus consists of three disulfide-bonded loop structures designated as the A B B\' motifs. G2 is similar to G1. The keratan sulfate (KS) and the chondroitin sulfate (CS) attachment domains lie between G2 and G3.
Ptm:	Contains mostly chondroitin sulfate but also keratan sulfate chains N-linked and O-linked oligosaccharides.
Similarity:	Belongs to the aggrecan/versican proteoglycan family.
Similarity:	Contains 1 C-type lectin domain.
Similarity:	Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Similarity:	Contains 4 Link domains.
Similarity:	Contains 1 Sushi (CCP/SCR) domain.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 2 ml

available

Delivery expected until 9/25/2025

Express Delivery: Save 8 days

Compare

Add to wishlist

Get an offer