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PROTEIN KINASE C ALPHA

PROTEIN KINASE C ALPHA

Item no.	20-783-70710
Manufacturer	GENWAY
Amount	2 ml
Category	Oncology Neuroscience Metabolism Diabetes Targets for Rodent Neurosciences Neural Signaling Antibodies By Cell Type Melanoma Immunohistochemistry Western Blot Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody
Applications	WB, IHC
Clone	133
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-FA9878
Similar products	20-783-70710
Available
Genway ID:	GWB-FA9878
Specificity:	PROTEIN KINASE C ALPHA
Specificity:	PROTEIN KINASE C ALPHA
Clone:	133
Immunogen:	Protein kinase C alpha
Fusion Partner:	Spleen cells from immunised mice were fused with cells of the mouse SP2/0 myeloma cell line.
Specificity Note:	This product recognises the a isoform of protein kinase C. This antibody recognises the sequence PQFVHPILQSAV at the C terminus of PKCa.
Preservative Stabilisers:		0. 09%Sodium AzideSuggested
Dilution:	Suggested
Dilution:	Immunohistology - Frozen - Nt - 1/10Western Blotting - 1/10 - 1/500
Function:	This is a calcium-activated phospholipid-dependent serine- and threonine-specific enzyme. May play a role in cell motility by phosphorylating CSPG4.
Function:	PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters a class of tumor promoters.
Catalytic Activity:	ATP + a protein = ADP + a phosphoprotein. Cofactor: Binds 3 calcium ions per subunit. The ions are bound to the C2 domain (By similarity).
Subunit:	Interacts with CENTA1 CSPG4 and PRKCABP. Binds to SDPR in the presence of phosphatidylserine.
Similarity:	Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
Similarity:	Contains 1 AGC-kinase C-terminal domain.
Similarity:	Contains 1 C2 domain.
Similarity:	Contains 2 phorbol-ester/DAG-type zinc fingers.
Similarity:	Contains 1 protein kinase domain.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 2 ml

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Delivery expected until 8/28/2025

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