GRANZYME B

GWB-596FB6

3002

GB10

Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.

Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant

ELISA - 1ug/ml Summary: Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize bind and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface \' nonself\' antigens usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. Summary: Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize bind and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface \' nonself\' antigens usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq]. 1. Spaeny-Dekking. E. H. A. et al. (1998) Extracellular Granzymes A and B in humans: Detection of native species during CTL responses in vitro and in vivo.