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IGFBP-3

IGFBP-3


Item no.	20-783-72936
Manufacturer	GENWAY
Amount	0.2 mg
Category	Oncology Metabolism Diabetes Antibodies Cell Biology Cell Status ELISA Senescence Primary Antibodies By Organ Thyroid Cancer
Type	Antibody
Applications	ELISA
Clone	7D9
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-D74C58
Similar products	20-783-72936
Available
Genway ID:	GWB-D74C58
Specificity:	IGFBP-3
Specificity:	IGFBP-3
Clone:	7D9
Immunogen:	R-DNA
Preparation:	Purified IgG prepared by affinity chromatography on Protein A
Buffer Solution:	Phosphate buffered saline
Preservative Stabilisers:		0. 04% Sodium Azide (NaN3)
Function:	IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Subunit:	Interacts with XLKD1 (By similarity). Binds IGF2 more than IGF1. Forms a ternary complex of about 140 to 150 kDa with IGF1 or IGF2 and a 85 kDa glycoprotein (ALS). Interacts with HN.
Subcellular Location:	Secreted.
Tissue Specificity:	Expressed by most tissues. Developmental Stage: IGFBP3 levels are higher during extrauterine life and peak during puberty.
Induction:	IGFBP3 levels increase in the presence of IGF1 insulin and other growth-stimulating factors such as growth hormone epidermal growth factor and phorbol esters.
Domain:	The thyroglobulin type-1 domain mediates interaction with HN.
Similarity:	Contains 1 IGFBP N-terminal domain.
Similarity:	Contains 1 thyroglobulin type-1 domain.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.2 mg

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Delivery expected until 11/13/2025

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