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UROTENSIN II

UROTENSIN II


Item no.	20-783-75007
Manufacturer	GENWAY
Amount	0.2 mg
Category	Oncology Antibodies ELISA Cardiovascular Research Atherosclerosis Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody
Applications	ELISA
Clone	UII-9
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-4981E1
Similar products	20-783-75007
Available
Genway ID:	GWB-4981E1
Specificity:	UROTENSIN IINCBI
Gene ID:	10911
Specificity:	UROTENSIN II
Clone:	UII-9
Immunogen:	Human Urotensin II
Fusion Partner:	Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cell line.
Specificity Note:	This product detects Urotensin II (U-II) a cyclic heptapeptide that functions both as a potent vasoconstrictor and a neurotransmitter/neuromodulator. U-II circulates in the plasma as a zymogen and is activated by the urotensin converting enzyme. U-II is the endogenous ligand for the G-protein coupled receptor 14 (GPR14) recently renamed the UT receptor. Changes in the expression of U-II and its receptor have been associated with cardiovascular and renal diseases including atherosclerosis myocardial infarction and diabetic nephropathy.
Preparation:	Purified IgG prepared by affinity chromatography on Protein A
Buffer Solution:	Phosphate buffered saline pH7. 4
Preservative Stabilisers:		0. 09%Sodium Azide (NaN3)
Function:	Highly potent vasoconstrictor.
Subcellular Location:	Secreted.
Tissue Specificity:	Brain specific.
Similarity:	Belongs to the urotensin-2 family. 1. Watanabe. T. et al. (2006) Human urotensin II as a link between hypertension and coronary artery disease. 2. Nothacker. H. P. and Clark. S. (2005) From heart to mind. The urotensin II system and its evolving neurophysiological role. 3. Zhu. Y. C. et al. (2006) The role of urotensin II in cardiovascular and renal physiology and diseases.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.2 mg

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Delivery expected until 9/11/2025

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