CD90

CD90NCBI

CD90

Purified human brain Thy-1

This product recognises the human CD90 cell surface antigen a 25kD glycoprotein homologous to rat Thy1. The antigen is expressed by a subset of CD34+ve cells in the bone marrow and by prothymocytes within the thymus. CD90 is also expressed extensively within the brain. This product is routinely tested in flow cytometry on the MOLT4 cell line. Histology: Human Brain thymus

Phosphate buffered saline pH7. 4

Use 10ul of the suggested working dilution to label 106 cells in 100ul. Suggested

May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.

Contains 1 Ig-like V-type (immunoglobulin-like) domain. 1. McKenzie. J. L. and Fabre. J. W. (1981) Human Thy-1: Unusual localization and possible functional significance in lymphoid tissues. 2. Daar. A. S. and Fabre. J. W. (1981) Demonstration with monoclonal antibodies of an unusual mononuclear cell infiltrate and loss of normal epithelial membrane antigens in human breast carcinomas. 3. Yoshino. N. et al. (2000) Upgrading of flow cytometric analysis for absolute counts. cytokines and other antigenic molecules of Cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies. 4. Fiegal. H. C. et al. (2004) Stem-like cells in human hepatoblastoma. 5. Hagood. J. S. et al. (2005) Loss of fibroblast Thy-1 expression correlates with lung fibrogenesis.