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Myeloperoxidase (pANCA)

Myeloperoxidase (pANCA)

Manufacturer	GENWAY
Category	Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Cell Metabolism ELISA Oxidative Stress
Type	Proteins
Specific against	other
Applications	ELISA
Amount	1mg
Item no.	11-511-248402
eClass 6.1	34160400
eClass 9.0	42020190
Available
Alias	GWB-1E14C9
Genway ID:	GWB-1E14C9
Specificity:	Myeloperoxidase (pANCA)
Type of Product:	Purified Cardiac Markers
Inactivation:	Not applicablePreservatives: Proprietary Preservative
Buffer:	20mM Tris-HCl 0. 4M NaCl pH 7. 6 with 0. 1mM PMSF 0. 02% Lubrol. Applications Notes : ELISA 0. 5-1. 0ug/ml coating concentration. . After thawing mix thoroughly by vortexing before use. . Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Concentration:	Concentration is lot specific Myeloperoxidase (pANCA)
Function:	Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN MPO catalyzes the production of hypohalous acids primarily hypochlorous acid in physiologic situations and other toxic intermediates that greatly enhance PMN microbicidal activity.
Catalytic Activity:	Donor + H2O2 = oxidized donor + 2 H2O.
Catalytic Activity:	Cl- + H2O2 = HOCl + 2 H2O. Cofactor: Binds 1 calcium ion per heterodimer. Cofactor: Binds 1 heme B (iron-protoporphyrin IX) group covalently per heterodimer.
Subunit:	Tetramer of two light chains and two heavy chains.
Subcellular Location:	Lysosome.
Disease:	Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.
Similarity:	Belongs to the peroxidase family. XPO subfamily.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1mg

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Delivery expected until 7/12/2024

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