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Biotinylated Human GLP1R Protein, His,Avitag™

Biotinylated Human GLP1R Protein, His,Avitag™

Manufacturer	ACROBiosystems
Type	Proteins Recombinant
Specific against	Human
Format	Powder
Amount	200ug
Host	HEK293
Item no.	GLR-H82E3-200ug
Conjugate/Tag	Biotin-labeled; Tag: C-10×His & C-Avi
eClass 6.1	34160400
eClass 9.0	42020190
Available
Description	Biotinylated Human GLP1R Protein, His, Avitag (GLR-H82E3) is expressed from human 293 cells (HEK293). It contains AA Ala 21 - Glu 139 (Accession # P43220-1).
Name of the protein	GLP1R
Express Region of the protein	Ala 21 - Glu 139
Storage conditions	-20℃
Theoretical molecular weight	17.3 kDa
Special informations about the product	This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 17.3 kDa. The protein migrates as 30-34 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Presence of endotoxins	1.0 EU per μg
Background information about the protein	This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200ug

available

Delivery expected until 5/23/2024