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CASP2 Antibody (Center)

CASP2 Antibody (Center)

Item no.	ABC-AP1327c
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Cell Biology Cell Status Apoptosis Flow Cytometry Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, FC, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Lan,Q., Morton,L.M. Blood (2009) In press Shi,M., Vivian,C.J. Cell 136 (3), 508-520 (2009) Paroni,G., Henderson,C. J. Biol. Chem. 276 (24), 21907-21915 (2001) Tiso,N., Pallavicini,A. Biochem. Biophys. Res. Commun. 225 (3), 983-989 (1996)
NCBI	NP_001215.1,NP_116764.2,NP_116765.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Caspase-2,CASP-2,Neural precursor cell expressed developmentally down-regulated protein 2,NEDD-2,Protease ICH-1,Caspase-2 subunit p18,Caspase-2 subunit p13,Caspase-2 subunit p12,CASP2,ICH1,NEDD2
Similar products	Caspase-2, CASP2, CASP-2, ICH1, NEDD2, NEDD-2, Neural precursor cell expressed developmentally down-regulated protein 2, Protease ICH-1, Caspase-2 subunit p12, Caspase-2 subunit p13, Caspase-2 subunit p18
Available
Manufacturer - Category	Primary Antibodies; Cancer; Cell Biology; Metabolism
Manufacturer - Targets	This CASP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the Central region of human CASP2.
Bio Background	CASP2 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. The protein exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB18402
Gene Name	CASP2
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	50685
Antigen Source	HUMAN
Antigen Region	198-226
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	WB: 1:1000 IHC-P: 1:10~50 FC: 1:10~50
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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