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cIAP2 (BIRC3) Antibody (N-term)

cIAP2 (BIRC3) Antibody (N-term)

Item no.	ABC-AP6124a
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	BIRC3, API2, IAP1, MIHC, RNF49, Baculoviral IAP repeat-containing protein 3, Apoptosis inhibitor 2, C-IAP2, IAP homolog C, Inhibitor of apoptosis protein 1, RING finger protein 49, TNFR2-TRAF-signaling complex protein 1, IAP-1, 632-, hIAP-1, hIAP1
Available
Primary Accession	Q13489
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	BIRC3 is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain.
Bio References	Wang, Q., et al., J. Biol. Chem. 278(51):51091-51099 (2003). Suguro-Katayama, M., et al., Leukemia 17(12):2508-2512 (2003). Jonsson, G., et al., Anticancer Res. 23(4):3311-3316 (2003). Yang, Q.H., et al., Genes Dev. 17(12):1487-1496 (2003). Dai, Z., et al., Hum. Mol. Genet. 12(7):791-801 (2003).
Clonality	Polyclonal
Clone/Animal Names	RB2213
Gene ID	330
Gene Name	BIRC3
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	BIRC3 Antibody (S116) (Cat. #AP6124a) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the BIRC3 antibody detected the BIRC3 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	cIAP2 (BIRC3) antibody (N-term) (Cat. #AP6124a)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of cIAP2 (BIRC3) antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	NP_892007
Isotype	Rabbit Ig
Calculated MW	68372
Antigen Region	101-131
Antigen Source	HUMAN
Target/Specificity	This cIAP2 (BIRC3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-131 amino acids from the N-terminal region of human cIAP2 (BIRC3).
NCBI Accession	NP_001156.1; NP_892007.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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