Comparison

MMP19 Antibody (C-term)

Item no. ABC-AP6202a
Manufacturer Abcepta
Amount 400 ul
Category
Type Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications WB, FC, IHC-P
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products MMP19, MMP18, RASI, Matrix metalloproteinase-19, Matrix metalloproteinase RASI, Matrix metalloproteinase-18, MMP-19, MMP-18, 3424-
Available
Primary Accession
Q99542
Antigen Type
Synthetic Peptide
Application
FC, WB, IHC-P
Bio Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The function of MMP19 has not been determined. This gene was previously referred to as MMP18 but has been renamed matrix metalloproteinase 19 (MMP19).
Bio References
Sadowski, T., et al., Mol. Biol. Cell 14(11):4569-4580 (2003).
Impola, U., et al., Int. J. Cancer 103(6):709-716 (2003).
Mauch, S., et al., J. Immunol. 168(3):1244-1251 (2002).
Stracke, J.O., et al., J. Biol. Chem. 275(20):14809-14816 (2000).
Nagase, H., et al., J. Biol. Chem. 274(31):21491-21494 (1999).
Clonality
Polyclonal
Clone/Animal Names
RB02035
Gene ID
4327
Gene Name
MMP19
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Western blot analysis of hMMP19-R359 (Cat. #AP6202a) in K562 cell line lysates (35ug/lane). MMP19 (arrow) was detected using the purified Pab.
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
Formalin-fixed and paraffin-embedded human breast carcinoma with MMP19 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2
IHC-P
Dilution image 2
1:50~100
Legend image 3
Flow cytometric analysis of K562 cells using MMP19 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3
FC
Dilution image 3
1:10~50
Other Accession
NP_002420
Isotype
Rabbit Ig
Calculated MW
57357
Antigen Region
344-373
Antigen Source
HUMAN
Target/Specificity
This MMP19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-373 amino acids from the C-terminal region of human MMP19.
NCBI Accession
NP_001259030.1; NP_002420.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
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