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PINK1 (PARK6) Antibody (N-term T133)

PINK1 (PARK6) Antibody (N-term T133)

Item no.	ABC-AP6406A
Manufacturer	Abcepta
Amount	400 ul
Category	Neuroscience Neuroinflammation Neural Mitochondrial Function Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot Autophagy Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Rogaeva,E.,et al. Arch. Neurol. 61 (12), 1898-1904 (2004) Hatano,Y., et al. Ann. Neurol. 56 (3), 424-427 (2004) Healy,D.G., et al. Ann. Neurol. 56 (3), 329-335 (2004) Valente,E.M., et al. Science 304 (5674), 1158-1160 (2004) Nakajima,A., et al. Cancer Lett. 201 (2), 195-201 (2003) Unoki,M. and Nakamura,Y. Oncogene 20 (33), 4457-4465 (2001)
NCBI	NP_115785.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Serine/threonine-protein kinase PINK1,mitochondrial,BRPK,PTEN-induced putative kinase protein 1,PINK1
Similar products	PINK1, mitochondrial, Serine/threonine-protein kinase PINK1, BRPK, PTEN-induced putative kinase protein 1
Available
Manufacturer - Category	Primary Antibodies; Cardiovascular; Metabolism; Neuroscience; Signal Transduction; Autophagy; Mitochondrion; Mitochondrion outer membrane
Manufacturer - Targets	This PINK1 (PARK6) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-147 amino acids from the N-terminal region of human PINK1 (PARK6).
Bio Background	Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB07381
Gene Name	PINK1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	62769
Antigen Source	HUMAN
Antigen Region	118-147
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	WB: 1:1000 IHC-P: 1:50~100
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 12/4/2025

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