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PINK1 (PARK6) Antibody (N-term T133)

PINK1 (PARK6) Antibody (N-term T133)

Item no.	ABC-AP6406A
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PINK1, mitochondrial, Serine/threonine-protein kinase PINK1, BRPK, PTEN-induced putative kinase protein 1
Available
Primary Accession	Q9BXM7
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.
Bio References	Rogaeva, E., et al. Arch. Neurol. 61 (12), 1898-1904 (2004) Hatano, Y., et al. Ann. Neurol. 56 (3), 424-427 (2004) Healy, D.G., et al. Ann. Neurol. 56 (3), 329-335 (2004) Valente, E.M., et al. Science 304 (5674), 1158-1160 (2004) Nakajima, A., et al. Cancer Lett. 201 (2), 195-201 (2003) Unoki, M. and Nakamura, Y. Oncogene 20 (33), 4457-4465 (2001)
Clonality	Polyclonal
Clone/Animal Names	RB07381
Gene ID	65018
Gene Name	PINK1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Anti-Park6 (PINK1) Antibody (N-term) at 1:1000 dilution + A549 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 63 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2	IHC-P
Dilution image 2	1:50~100
Other Accession	NP_115785
Isotype	Rabbit Ig
Calculated MW	62769
Antigen Region	118-147
Antigen Source	HUMAN
Target/Specificity	This PINK1 (PARK6) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-147 amino acids from the N-terminal region of human PINK1 (PARK6).
NCBI Accession	NP_115785.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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