Comparison

DJ-1 Antibody (N-term)

Item no. ABC-AP6407a
Manufacturer Abcepta
Amount 400 ul
Category
Type Antibody Polyclonal
Applications WB, IF
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Citations Kim, R.H., et al., Cancer Cell 7(3):263-273 (2005). Shinbo, Y., et al., Int. J. Oncol. 26(3):641-648 (2005). Takahashi-Niki, K., et al., Biochem. Biophys. Res. Commun. 320(2):389-397 (2004). Hering, R., et al., Hum. Mutat. 24(4):321-329 (2004). Maraganore, D.M., et al., Neurology 63(3):550-553 (2004).
NCBI NP_001116849.1,NP_009193.2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Protein DJ-1,34--,Oncogene DJ1,Parkinson disease protein 7,PARK7
Similar products PARK7, Protein DJ-1, Oncogene DJ1, Parkinson disease protein 7, 34--
Available
Manufacturer - Category
Primary Antibodies; Cancer; Cell Biology; Metabolism; Neuroscience; Signal Transduction; Inflammatory response; Autophagy; Mitochondrion; Stress response
Manufacturer - Targets
This DJ-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DJ-1.
Bio Background
Park 7 acts as positive regulator of androgen receptor-dependent transcription, and may function as redox-sensitive chaperone and as sensor for oxidative stress, as well as preventing aggregation of SNCA. This protein has been shown to protect neurons against oxidative stress and cell death, and to play a role in fertilization. Park7 is detected in tau inclusions in brains from neurodegenerative disease patients, and is generally highly expressed in pancreas, kidney, skeletal muscle, liver, testis and heart, with detectable levels in placenta, brain, astrocytes, Sertoli cells, spermatogonia, spermatids and spermatozoa. Defects in Park7 are the cause of autosomal recessive early-onset Parkinson disease 7 (PARK7), a form of Parkinson disease characterized by onset before 4 years, slow progression and initial good response to levodopa.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB8160
Gene Name
PARK7
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H, M
Predicted Reactivity
B, Zf
Calculated Molecular Weight
19891
Antigen Source
HUMAN
Antigen Region
1-30
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution
IF: 1:10~50
WB: 1:2000
WB: 1:2000
Antigen Type
Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
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