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LATS2 Antibody (Center)

LATS2 Antibody (Center)

Item no.	ABC-AP7035C
Manufacturer	Abcepta
Amount	400 ul
Category	Oncology Antibodies Immunohistochemistry Primary Antibodies By Organ Lung Cancer Bladder Cancer Breast Cancer
Type	Antibody Polyclonal
Applications	IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Blume-Jensen P, et al. Nature 2001. 411: 355. Cantrell D, J. Cell Sci. 2001. 114: 1439. Jhiang S Oncogene 2000. 19: 5590. Manning G, et al. Science 2002. 298: 1912. Moller, D, et al. Am. J. Physiol. 1994. 266: C351-C359. Robertson, S. et al. Trends Genet. 2000. 16: 368. Robinson D, et al. Oncogene 2000. 19: 5548. Van der Ven, P, et al. Hum. Molec. Genet. 1993. 2: 1889. Vanhaesebroeck, B, et al. Biochem. J. 2000. 346: 561. Van Weering D, et al. Recent Results Cancer Res. 1998. 154: 271.
NCBI	NP_055387.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Serine/threonine-protein kinase LATS2,Kinase phosphorylated during mitosis protein,Large tumor suppressor homolog 2,Serine/threonine-protein kinase kpm,Warts-like kinase,LATS2 {ECO:0000312\|EMBL:BAA923811},KPM
Similar products	Serine/threonine-protein kinase LATS2, Kinase phosphorylated during mitosis protein, Large tumor suppressor homolog 2, Serine/threonine-protein kinase kpm, KPM, Warts-like kinase, LATS2 {ECO:0000312\|EMBL:BAA923811}
Available
Manufacturer - Category	Primary Antibodies; Cancer; Cell Biology; Signal Transduction; Catalog Updated
Manufacturer - Targets	This LATS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-258 amino acids from the Central region of human LATS2.
Bio Background	LATS2 is a serine/threonine protein kinase belonging to the LATS tumor suppressor family. This protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB3032
Gene Name	LATS2 {ECO:0000312\|EMBL:BAA92381.1}
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	120136
Antigen Source	HUMAN
Antigen Region	228-258
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	IHC-P: 1:10~50
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 2/5/2026

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