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CDK2 Antibody (T14)

CDK2 Antibody (T14)

Item no.	ABC-AP7518d
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	CDK2, p33 protein kinase, Cyclin-dependent kinase 2, Cell division protein kinase 2, CDKN2
Available
Primary Accession	P24941
Antigen Type	Synthetic Peptide
Application	WB, IHC-P
Bio Background	CDK2 is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation.
Bio References	Moshinsky, D.J., et al., Biochem. Biophys. Res. Commun. 310(3):1026-1031 (2003). Chow, J.P., et al., J. Biol. Chem. 278(42):40815-40828 (2003). O'Nions, J., et al., Oncogene 22(46):7181-7191 (2003). Yun, J., et al., J. Biol. Chem. 278(38):36966-36972 (2003). Izumiya, Y., et al., J. Virol. 77(17):9652-9661 (2003).
Clonality	Polyclonal
Clone/Animal Names	RB7918
Gene ID	1017
Gene Name	CDK2
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Cdk2 Antibody (T14) (Cat. #AP7518d) western blot analysis in 293, Hela cell line lysates (35ug/lane).This demonstrates the hCdk2 antibody detected the hCdk2 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with CDK2 Antibody (T14) (Cat.#AP7518d), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	Q80YP0; Q00526; P23437; Q63699; P97377; O55076; Q5E9Y0
Predicted	B, Ha, M, Rat, X
Isotype	Rabbit Ig
Calculated MW	33930
Antigen Region	1-30
Antigen Source	HUMAN
Target/Specificity	This CDK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from human CDK2.
NCBI Accession	NP_001789.2; NP_439892.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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